Effect of paliperidone palmitate treatment on disease family burden and rehabilitation effect in community schizophrenic patients
ObjectiveTo explore the effect of paliperidone palmitate treatment on schizophrenic patients in the community.Methods446 schizophrenic patients who used paliperidone palmitate injection were selected in Shanghai. Before and after the treatment， the disease family burden scale， the concise evaluation...
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| Format: | Article |
| Language: | zho |
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Shanghai Preventive Medicine Association
2023-07-01
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| Series: | Shanghai yufang yixue |
| Subjects: | |
| Online Access: | http://www.sjpm.org.cn/article/doi/10.19428/j.cnki.sjpm.2023.22729 |
| _version_ | 1797660767878643712 |
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| author | GE Xiaolei ZHANG Weibo CHEN Chunmei HE Siyuan ZHAO Miaomiao JIN Jin XIE Bin CAI Jun ZHU Yi |
| author_facet | GE Xiaolei ZHANG Weibo CHEN Chunmei HE Siyuan ZHAO Miaomiao JIN Jin XIE Bin CAI Jun ZHU Yi |
| author_sort | GE Xiaolei |
| collection | DOAJ |
| description | ObjectiveTo explore the effect of paliperidone palmitate treatment on schizophrenic patients in the community.Methods446 schizophrenic patients who used paliperidone palmitate injection were selected in Shanghai. Before and after the treatment， the disease family burden scale， the concise evaluation scale of drug treatment compliance， the VAS100 score of treatment satisfaction， the short form of quality of life measurement scale， and the screening scale of social function defects were used to evaluate the effects of paliperidone palmitate injection. The data were statistically analyzed using SPSS 26.0 software.ResultsAfter using paliperidone palmitate injection， the total score of family burden （13.94±12.17）， the score of daily family activities （3.26±2.74）， the score of family entertainment activities （2.21±2.30）， and the score of family relationship （2.79±2.76） were significantly higher than those before the treatment （14.98±12.64， 3.51±2.88， 2.48±2.38， 3.11±2.87， respectively， all with P<0.05）. The scores of the World Health Organization on quality of life brief scale （62.89±11.94） and the medication compliance scale （28.11±5.64） were better than those before treatment （60.67±12.62 and 27.37±6.96， all with P<0.05）. Compared with the prior treatment without paliperidone palmitate injection， the number of readmissions after treatment was significantly reduced （P<0.01）.ConclusionThe treatment of paliperidone palmitate injection has significant effect， which can effectively reduce the disease family burden of Schizophrenic patients， improve their quality of life， enhance their drug compliance， reduce the readmission rate of patients， ensure long-term treatment effect and promote disease recovery. |
| first_indexed | 2024-03-11T18:34:48Z |
| format | Article |
| id | doaj.art-3ce4dc3177fc48e592dade0c64b5ac54 |
| institution | Directory Open Access Journal |
| issn | 1004-9231 |
| language | zho |
| last_indexed | 2024-03-11T18:34:48Z |
| publishDate | 2023-07-01 |
| publisher | Shanghai Preventive Medicine Association |
| record_format | Article |
| series | Shanghai yufang yixue |
| spelling | doaj.art-3ce4dc3177fc48e592dade0c64b5ac542023-10-13T02:42:16ZzhoShanghai Preventive Medicine AssociationShanghai yufang yixue1004-92312023-07-0135768468810.19428/j.cnki.sjpm.2023.227291004-9231（2023）07-0684-05Effect of paliperidone palmitate treatment on disease family burden and rehabilitation effect in community schizophrenic patientsGE Xiaolei0ZHANG Weibo1CHEN Chunmei2HE Siyuan3ZHAO Miaomiao4JIN Jin5XIE Bin6CAI Jun7ZHU Yi8Shanghai Mental Health Center， Shanghai Jiao Tong University School of Medicine， Shanghai 200030， ChinaShanghai Mental Health Center， Shanghai Jiao Tong University School of Medicine， Shanghai 200030， ChinaShanghai Mental Health Center， Shanghai Jiao Tong University School of Medicine， Shanghai 200030， ChinaShanghai Mental Health Center， Shanghai Jiao Tong University School of Medicine， Shanghai 200030， ChinaShanghai Mental Health Center， Shanghai Jiao Tong University School of Medicine， Shanghai 200030， ChinaShanghai Mental Health Center， Shanghai Jiao Tong University School of Medicine， Shanghai 200030， ChinaShanghai Mental Health Center， Shanghai Jiao Tong University School of Medicine， Shanghai 200030， ChinaShanghai Mental Health Center， Shanghai Jiao Tong University School of Medicine， Shanghai 200030， ChinaShanghai Mental Health Center， Shanghai Jiao Tong University School of Medicine， Shanghai 200030， ChinaObjectiveTo explore the effect of paliperidone palmitate treatment on schizophrenic patients in the community.Methods446 schizophrenic patients who used paliperidone palmitate injection were selected in Shanghai. Before and after the treatment， the disease family burden scale， the concise evaluation scale of drug treatment compliance， the VAS100 score of treatment satisfaction， the short form of quality of life measurement scale， and the screening scale of social function defects were used to evaluate the effects of paliperidone palmitate injection. The data were statistically analyzed using SPSS 26.0 software.ResultsAfter using paliperidone palmitate injection， the total score of family burden （13.94±12.17）， the score of daily family activities （3.26±2.74）， the score of family entertainment activities （2.21±2.30）， and the score of family relationship （2.79±2.76） were significantly higher than those before the treatment （14.98±12.64， 3.51±2.88， 2.48±2.38， 3.11±2.87， respectively， all with P<0.05）. The scores of the World Health Organization on quality of life brief scale （62.89±11.94） and the medication compliance scale （28.11±5.64） were better than those before treatment （60.67±12.62 and 27.37±6.96， all with P<0.05）. Compared with the prior treatment without paliperidone palmitate injection， the number of readmissions after treatment was significantly reduced （P<0.01）.ConclusionThe treatment of paliperidone palmitate injection has significant effect， which can effectively reduce the disease family burden of Schizophrenic patients， improve their quality of life， enhance their drug compliance， reduce the readmission rate of patients， ensure long-term treatment effect and promote disease recovery.http://www.sjpm.org.cn/article/doi/10.19428/j.cnki.sjpm.2023.22729schizophreniapaliperidone palmitate injectioncommunitydisease family burdenrehabilitation |
| spellingShingle | GE Xiaolei ZHANG Weibo CHEN Chunmei HE Siyuan ZHAO Miaomiao JIN Jin XIE Bin CAI Jun ZHU Yi Effect of paliperidone palmitate treatment on disease family burden and rehabilitation effect in community schizophrenic patients Shanghai yufang yixue schizophrenia paliperidone palmitate injection community disease family burden rehabilitation |
| title | Effect of paliperidone palmitate treatment on disease family burden and rehabilitation effect in community schizophrenic patients |
| title_full | Effect of paliperidone palmitate treatment on disease family burden and rehabilitation effect in community schizophrenic patients |
| title_fullStr | Effect of paliperidone palmitate treatment on disease family burden and rehabilitation effect in community schizophrenic patients |
| title_full_unstemmed | Effect of paliperidone palmitate treatment on disease family burden and rehabilitation effect in community schizophrenic patients |
| title_short | Effect of paliperidone palmitate treatment on disease family burden and rehabilitation effect in community schizophrenic patients |
| title_sort | effect of paliperidone palmitate treatment on disease family burden and rehabilitation effect in community schizophrenic patients |
| topic | schizophrenia paliperidone palmitate injection community disease family burden rehabilitation |
| url | http://www.sjpm.org.cn/article/doi/10.19428/j.cnki.sjpm.2023.22729 |
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