Identification of active natural products that induce lysosomal biogenesis by lysosome-based screening and biological evaluation

Identification of active natural products that induce lysosomal biogenesis by lysosome-based screening and biological evaluation

Lysosomal biogenesis is an essential adaptive process by which lysosomes exert their function in maintaining cellular homeostasis. Defects in lysosomal enzymes and functions lead to lysosome-related diseases, including lysosomal storage diseases and neurodegenerative disorders. Thus, activation of t...

Full description

Bibliographic Details
Main Authors: Xiao Ding, Xu Yang, Yueqin Zhao, Yinyuan Wang, Jimin Fei, Zhenpeng Niu, Xianxiang Dong, Xuenan Wang, Biao Liu, Hongmei Li, Xiaojiang Hao, Yuhan Zhao
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:Heliyon
Subjects:
Lysosomal biogenesis
Natural products
TFEB and TFE3
Lysosome-based screening
Autophagy
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844022024677

Similar Items

Similar Items