Imaging Characteristics of Breast Lymphoma; a Case Series

Introduction: Breast involvement by lymphoma is rare. It can occur as a primary breast tumour or as an extranodal manifestation of the systemic disease. The imaging features of breast lymphoma (BL) are not characteristic. Biopsy is necessary for diagnosis due to non-specific imaging features. Materi...

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Main Authors: Sara Rehman, Muhammad Atif Naveed, Javairia Aleem
Format: Article
Language:English
Published: Shaukat Khanum Memorial Trust 2020-01-01
Series:Journal of Cancer and Allied Specialties
Subjects:
Online Access:http://journals.sfu.ca/jcas/index.php/jcas/article/view/305
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author Sara Rehman
Muhammad Atif Naveed
Javairia Aleem
author_facet Sara Rehman
Muhammad Atif Naveed
Javairia Aleem
author_sort Sara Rehman
collection DOAJ
description Introduction: Breast involvement by lymphoma is rare. It can occur as a primary breast tumour or as an extranodal manifestation of the systemic disease. The imaging features of breast lymphoma (BL) are not characteristic. Biopsy is necessary for diagnosis due to non-specific imaging features. Materials and Methods: A retrospective electronic medical chart review was conducted of patients diagnosed with lymphoma of breast that underwent diagnostic radiological procedures (including mammography, ultrasound breast, computed tomography (CT) scan and positron emission tomography (PET/CT) scan from 1 July 2018 to 31 March 2019 at Shaukat Khanum Memorial Cancer Hospital and Research Centre, Pakistan. Results: Four patients were identified. On mammogram, the most common finding consisted of the presence of high-density masses with circumscribed or indistinct margins. On ultrasound, hypoechoic masses and indistinct diffuse infiltrative patterns were observed. PET/CT and CT were helpful in detecting extramammary sites of disease and for classifying the disease into primary or secondary BL. Conclusion: The early diagnosis of the BL is important. The radiologists should include lymphoma in the differential diagnosis when there is the absence of microcalcifications or spiculated margins on mammography and ultrasound.
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spelling doaj.art-3cea0935d2aa4a32a42f23a9dfb410222022-12-21T20:04:19ZengShaukat Khanum Memorial TrustJournal of Cancer and Allied Specialties2411-989X2020-01-016110.37029/jcas.v6i1.305Imaging Characteristics of Breast Lymphoma; a Case SeriesSara Rehman0Muhammad Atif NaveedJavairia AleemShaukat Khanum Cancer Hospital and Research Centre.Introduction: Breast involvement by lymphoma is rare. It can occur as a primary breast tumour or as an extranodal manifestation of the systemic disease. The imaging features of breast lymphoma (BL) are not characteristic. Biopsy is necessary for diagnosis due to non-specific imaging features. Materials and Methods: A retrospective electronic medical chart review was conducted of patients diagnosed with lymphoma of breast that underwent diagnostic radiological procedures (including mammography, ultrasound breast, computed tomography (CT) scan and positron emission tomography (PET/CT) scan from 1 July 2018 to 31 March 2019 at Shaukat Khanum Memorial Cancer Hospital and Research Centre, Pakistan. Results: Four patients were identified. On mammogram, the most common finding consisted of the presence of high-density masses with circumscribed or indistinct margins. On ultrasound, hypoechoic masses and indistinct diffuse infiltrative patterns were observed. PET/CT and CT were helpful in detecting extramammary sites of disease and for classifying the disease into primary or secondary BL. Conclusion: The early diagnosis of the BL is important. The radiologists should include lymphoma in the differential diagnosis when there is the absence of microcalcifications or spiculated margins on mammography and ultrasound.http://journals.sfu.ca/jcas/index.php/jcas/article/view/305Breast lymphomacase seriesmammogrampositron emission tomography / computed tomography imaging (PET/CT)ultrasound
spellingShingle Sara Rehman
Muhammad Atif Naveed
Javairia Aleem
Imaging Characteristics of Breast Lymphoma; a Case Series
Journal of Cancer and Allied Specialties
Breast lymphoma
case series
mammogram
positron emission tomography / computed tomography imaging (PET/CT)
ultrasound
title Imaging Characteristics of Breast Lymphoma; a Case Series
title_full Imaging Characteristics of Breast Lymphoma; a Case Series
title_fullStr Imaging Characteristics of Breast Lymphoma; a Case Series
title_full_unstemmed Imaging Characteristics of Breast Lymphoma; a Case Series
title_short Imaging Characteristics of Breast Lymphoma; a Case Series
title_sort imaging characteristics of breast lymphoma a case series
topic Breast lymphoma
case series
mammogram
positron emission tomography / computed tomography imaging (PET/CT)
ultrasound
url http://journals.sfu.ca/jcas/index.php/jcas/article/view/305
work_keys_str_mv AT sararehman imagingcharacteristicsofbreastlymphomaacaseseries
AT muhammadatifnaveed imagingcharacteristicsofbreastlymphomaacaseseries
AT javairiaaleem imagingcharacteristicsofbreastlymphomaacaseseries