Anticholinergic action is rarely a good thing

The evidence for the risks associated with anticholinergic agents has grown considerably in the last two decades. Not only are they associated with causing peripheral side effects such as dry mouth, blurred vision and constipation, but they can also cause central effects such as cognitive impairment...

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Main Author: Delia Bishara
Format: Article
Language:English
Published: SAGE Publishing 2023-09-01
Series:Therapeutic Advances in Psychopharmacology
Online Access:https://doi.org/10.1177/20451253231195264
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author Delia Bishara
author_facet Delia Bishara
author_sort Delia Bishara
collection DOAJ
description The evidence for the risks associated with anticholinergic agents has grown considerably in the last two decades. Not only are they associated with causing peripheral side effects such as dry mouth, blurred vision and constipation, but they can also cause central effects such as cognitive impairment; and more recently, they have consistently been linked with an increased risk of dementia and death in older people. This paper reviews the evidence for the associations of anticholinergic agents and the risk of dementia and increased mortality in dementia.
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spelling doaj.art-3cee57ab4cbe498e9c429ac389393c8b2023-09-09T16:03:23ZengSAGE PublishingTherapeutic Advances in Psychopharmacology2045-12612023-09-011310.1177/20451253231195264Anticholinergic action is rarely a good thingDelia BisharaThe evidence for the risks associated with anticholinergic agents has grown considerably in the last two decades. Not only are they associated with causing peripheral side effects such as dry mouth, blurred vision and constipation, but they can also cause central effects such as cognitive impairment; and more recently, they have consistently been linked with an increased risk of dementia and death in older people. This paper reviews the evidence for the associations of anticholinergic agents and the risk of dementia and increased mortality in dementia.https://doi.org/10.1177/20451253231195264
spellingShingle Delia Bishara
Anticholinergic action is rarely a good thing
Therapeutic Advances in Psychopharmacology
title Anticholinergic action is rarely a good thing
title_full Anticholinergic action is rarely a good thing
title_fullStr Anticholinergic action is rarely a good thing
title_full_unstemmed Anticholinergic action is rarely a good thing
title_short Anticholinergic action is rarely a good thing
title_sort anticholinergic action is rarely a good thing
url https://doi.org/10.1177/20451253231195264
work_keys_str_mv AT deliabishara anticholinergicactionisrarelyagoodthing