Zootechnical performance, degree of steatosis and the genotoxic potential in yellowtail tetra Astyanax lacustris fed with different levels of L-carnitine
ABSTRACT L-carnitine perform a major role in transporting long-chain fatty acids into the mitochondria, where they are oxidized. It has been used in animal diets to decrease fat and increase muscle protein. The aim of this study was to evaluate the zootechnical performance, degree of steatosis in th...
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| Format: | Article |
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Universidade Federal de Minas Gerais
2023-07-01
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| Series: | Arquivo Brasileiro de Medicina Veterinária e Zootecnia |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352023000400753&lng=en&tlng=en |
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| author | L.F. Martins W.V. Silva N.F. Nascimento M.P. Melo B.A. Crispim A. Barufatti C.C. Hilbig |
| author_facet | L.F. Martins W.V. Silva N.F. Nascimento M.P. Melo B.A. Crispim A. Barufatti C.C. Hilbig |
| author_sort | L.F. Martins |
| collection | DOAJ |
| description | ABSTRACT L-carnitine perform a major role in transporting long-chain fatty acids into the mitochondria, where they are oxidized. It has been used in animal diets to decrease fat and increase muscle protein. The aim of this study was to evaluate the zootechnical performance, degree of steatosis in the liver, and genotoxic potential in Astyanax lacustris fed with different levels of L-carnitine (LC). Yellowtail tetra juveniles (n = 140) were distributed in 20 tanks of 70 L, with seven fish in each, in a water recirculation system with controlled temperature (27±0.1⁰C). The treatments with different levels of L-carnitine supplementation were: 0 (control), 250, 500, 750, and 1000 mg of LC per kg of food. The diets were provided twice a day for 60 days. The results showed that the different levels of LC did not affect (P>0.05) weight gain, survival, viscerosomatic index, and the liver hepatocytes showed a normal appearance. However, the use of LC supplementation showed genotoxic potential with a significant difference (P<0.05) for cell alterations when compared to the control at concentrations above 500mg kg-1. |
| first_indexed | 2024-03-12T23:10:23Z |
| format | Article |
| id | doaj.art-3cf25df32c25451d820ed8028ffa3a99 |
| institution | Directory Open Access Journal |
| issn | 1678-4162 |
| language | English |
| last_indexed | 2024-03-12T23:10:23Z |
| publishDate | 2023-07-01 |
| publisher | Universidade Federal de Minas Gerais |
| record_format | Article |
| series | Arquivo Brasileiro de Medicina Veterinária e Zootecnia |
| spelling | doaj.art-3cf25df32c25451d820ed8028ffa3a992023-07-18T07:43:31ZengUniversidade Federal de Minas GeraisArquivo Brasileiro de Medicina Veterinária e Zootecnia1678-41622023-07-0175475375810.1590/1678-4162-12934Zootechnical performance, degree of steatosis and the genotoxic potential in yellowtail tetra Astyanax lacustris fed with different levels of L-carnitineL.F. Martinshttps://orcid.org/0000-0002-3808-3011W.V. Silvahttps://orcid.org/0000-0003-1145-5951N.F. Nascimentohttps://orcid.org/0000-0002-0515-3431M.P. Melohttps://orcid.org/0000-0003-0553-8099B.A. Crispimhttps://orcid.org/0000-0003-0606-4905A. Barufattihttps://orcid.org/0000-0001-8789-2117C.C. Hilbighttps://orcid.org/0000-0002-2897-6684ABSTRACT L-carnitine perform a major role in transporting long-chain fatty acids into the mitochondria, where they are oxidized. It has been used in animal diets to decrease fat and increase muscle protein. The aim of this study was to evaluate the zootechnical performance, degree of steatosis in the liver, and genotoxic potential in Astyanax lacustris fed with different levels of L-carnitine (LC). Yellowtail tetra juveniles (n = 140) were distributed in 20 tanks of 70 L, with seven fish in each, in a water recirculation system with controlled temperature (27±0.1⁰C). The treatments with different levels of L-carnitine supplementation were: 0 (control), 250, 500, 750, and 1000 mg of LC per kg of food. The diets were provided twice a day for 60 days. The results showed that the different levels of LC did not affect (P>0.05) weight gain, survival, viscerosomatic index, and the liver hepatocytes showed a normal appearance. However, the use of LC supplementation showed genotoxic potential with a significant difference (P<0.05) for cell alterations when compared to the control at concentrations above 500mg kg-1.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352023000400753&lng=en&tlng=encells alterationsfishfood additivenutrition |
| spellingShingle | L.F. Martins W.V. Silva N.F. Nascimento M.P. Melo B.A. Crispim A. Barufatti C.C. Hilbig Zootechnical performance, degree of steatosis and the genotoxic potential in yellowtail tetra Astyanax lacustris fed with different levels of L-carnitine Arquivo Brasileiro de Medicina Veterinária e Zootecnia cells alterations fish food additive nutrition |
| title | Zootechnical performance, degree of steatosis and the genotoxic potential in yellowtail tetra Astyanax lacustris fed with different levels of L-carnitine |
| title_full | Zootechnical performance, degree of steatosis and the genotoxic potential in yellowtail tetra Astyanax lacustris fed with different levels of L-carnitine |
| title_fullStr | Zootechnical performance, degree of steatosis and the genotoxic potential in yellowtail tetra Astyanax lacustris fed with different levels of L-carnitine |
| title_full_unstemmed | Zootechnical performance, degree of steatosis and the genotoxic potential in yellowtail tetra Astyanax lacustris fed with different levels of L-carnitine |
| title_short | Zootechnical performance, degree of steatosis and the genotoxic potential in yellowtail tetra Astyanax lacustris fed with different levels of L-carnitine |
| title_sort | zootechnical performance degree of steatosis and the genotoxic potential in yellowtail tetra astyanax lacustris fed with different levels of l carnitine |
| topic | cells alterations fish food additive nutrition |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352023000400753&lng=en&tlng=en |
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