Is the frontal sinus immune to carcinoma? A retrospective study and review of the literature

Abstract Background Frontal sinus carcinoma is commonly seen as an extension of the ethmoid sinus, overlying skin, or lacrimal gland. The existence of this disease has been unclear. We aimed to describe the occurrence of primary frontal sinus carcinoma. Methods We conducted a systematic literature r...

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Main Authors: Mohamed Rifai, Maha Zaki, M. E. Abdelmalek
Format: Article
Language:English
Published: SpringerOpen 2023-08-01
Series:The Egyptian Journal of Otolaryngology
Subjects:
Online Access:https://doi.org/10.1186/s43163-023-00488-y
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author Mohamed Rifai
Maha Zaki
M. E. Abdelmalek
author_facet Mohamed Rifai
Maha Zaki
M. E. Abdelmalek
author_sort Mohamed Rifai
collection DOAJ
description Abstract Background Frontal sinus carcinoma is commonly seen as an extension of the ethmoid sinus, overlying skin, or lacrimal gland. The existence of this disease has been unclear. We aimed to describe the occurrence of primary frontal sinus carcinoma. Methods We conducted a systematic literature review and a retrospective review of the medical records at our institution in the past 10 years. Results Sixty-four articles were included in the literature review. Most frontal sinus carcinomas involved surrounding structures as the sphenoid or ethmoid sinus, and a primary origin in the frontal sinus could not be confirmed. No cases of primary frontal sinus carcinoma were identified at our hospital. Conclusion Isolated primary frontal sinus carcinoma, if exists, is very rare. There is uncertainty regarding the primary origin of frontal sinus carcinoma in most studies. The frontal sinus seems to be immune from primary carcinoma. Further studies are needed to explain such immunity.
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spelling doaj.art-3cf272a22df14d3bba4269737413cb3c2024-04-28T10:08:11ZengSpringerOpenThe Egyptian Journal of Otolaryngology2090-85392023-08-013911610.1186/s43163-023-00488-yIs the frontal sinus immune to carcinoma? A retrospective study and review of the literatureMohamed Rifai0Maha Zaki1M. E. Abdelmalek2Department of Otolaryngology, Kasr El Aini Hospital, Cairo UniversityDepartment of Otolaryngology, Kasr El Aini Hospital, Cairo UniversityDepartment of Otolaryngology, Kasr El Aini Hospital, Cairo UniversityAbstract Background Frontal sinus carcinoma is commonly seen as an extension of the ethmoid sinus, overlying skin, or lacrimal gland. The existence of this disease has been unclear. We aimed to describe the occurrence of primary frontal sinus carcinoma. Methods We conducted a systematic literature review and a retrospective review of the medical records at our institution in the past 10 years. Results Sixty-four articles were included in the literature review. Most frontal sinus carcinomas involved surrounding structures as the sphenoid or ethmoid sinus, and a primary origin in the frontal sinus could not be confirmed. No cases of primary frontal sinus carcinoma were identified at our hospital. Conclusion Isolated primary frontal sinus carcinoma, if exists, is very rare. There is uncertainty regarding the primary origin of frontal sinus carcinoma in most studies. The frontal sinus seems to be immune from primary carcinoma. Further studies are needed to explain such immunity.https://doi.org/10.1186/s43163-023-00488-yFrontal sinusParanasal sinus neoplasms
spellingShingle Mohamed Rifai
Maha Zaki
M. E. Abdelmalek
Is the frontal sinus immune to carcinoma? A retrospective study and review of the literature
The Egyptian Journal of Otolaryngology
Frontal sinus
Paranasal sinus neoplasms
title Is the frontal sinus immune to carcinoma? A retrospective study and review of the literature
title_full Is the frontal sinus immune to carcinoma? A retrospective study and review of the literature
title_fullStr Is the frontal sinus immune to carcinoma? A retrospective study and review of the literature
title_full_unstemmed Is the frontal sinus immune to carcinoma? A retrospective study and review of the literature
title_short Is the frontal sinus immune to carcinoma? A retrospective study and review of the literature
title_sort is the frontal sinus immune to carcinoma a retrospective study and review of the literature
topic Frontal sinus
Paranasal sinus neoplasms
url https://doi.org/10.1186/s43163-023-00488-y
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