Efficacy of CT Guided Pulsed Radiofrequency Treatment for Trigeminal Postherpetic Neuralgia
ObjectivesTrigeminal postherpetic neuralgia (TPHN) often presents with moderate to severe pain, hyperalgesia, and allodynia. Conventional analgesic treatments are poorly effective, which seriously affects the quality of life. This retrospective study aimed to evaluate the efficacy of pulsed radiofre...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2019-07-01
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| Series: | Frontiers in Neuroscience |
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| Online Access: | https://www.frontiersin.org/article/10.3389/fnins.2019.00708/full |
| _version_ | 1819068218302529536 |
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| author | Yuanyuan Ding Tao Hong Hongxi Li Peng Yao Guangyi Zhao |
| author_facet | Yuanyuan Ding Tao Hong Hongxi Li Peng Yao Guangyi Zhao |
| author_sort | Yuanyuan Ding |
| collection | DOAJ |
| description | ObjectivesTrigeminal postherpetic neuralgia (TPHN) often presents with moderate to severe pain, hyperalgesia, and allodynia. Conventional analgesic treatments are poorly effective, which seriously affects the quality of life. This retrospective study aimed to evaluate the efficacy of pulsed radiofrequency (PRF) for the treatment of TPHN.MethodsA total of 90 TPHN patients were selected between January 2014 and December 2016 in the Department of Pain Management, Shengjing Hospital, China Medical University. Patients were randomly divided into two groups according to the order of enrollment (n = 45 per group): group A, peripheral nerve (supraorbital nerve, infraorbital nerve and mental nerve) PRF; group B, gasserian ganglion PRF. Follow-up assessments of visual analogue scale (VAS) pain assessment, SF-36 health status questionnaire, total efficiency rate, and drug dosage of anticonvulsants and opioid analgesics were performed at time points of 1 week, 1 month, 3 months, 6 months, and 1 year after surgery.ResultsAt each postsurgery time point, the VAS decreased, SF-36 (physical and mental components) increased, and drug dosage of anticonvulsants and opioids analgesics decreased in both treatment groups; values at each time point were significantly different from presurgery values (P < 0.05). Compared with group A, VAS decreased, SF-36 increased, and dosage of anticonvulsants and opioids analgesics decreased significantly in group B (P < 0.05). The total efficiency rates one year after surgery in group A and group B were 68.9 and 86.7%, respectively. The total efficiency rate of group B was statistically higher than that of group A (P < 0.05).ConclusionPRF relieved TPHN, and gasserian ganglion PRF was more effective than peripheral nerve PRF. The method was effective and improved the quality of life of the patients. PRF is recommended as a treatment for TPHN. |
| first_indexed | 2024-12-21T16:30:39Z |
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| institution | Directory Open Access Journal |
| issn | 1662-453X |
| language | English |
| last_indexed | 2024-12-21T16:30:39Z |
| publishDate | 2019-07-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neuroscience |
| spelling | doaj.art-3cf28b950bdc4a5fbfad1707fde3b3382022-12-21T18:57:21ZengFrontiers Media S.A.Frontiers in Neuroscience1662-453X2019-07-011310.3389/fnins.2019.00708465848Efficacy of CT Guided Pulsed Radiofrequency Treatment for Trigeminal Postherpetic NeuralgiaYuanyuan Ding0Tao Hong1Hongxi Li2Peng Yao3Guangyi Zhao4Department of Pain Management, Shengjing Hospital of China Medical University, Shenyang, ChinaDepartment of Pain Management, Shengjing Hospital of China Medical University, Shenyang, ChinaDepartment of Pain Management, Shengjing Hospital of China Medical University, Shenyang, ChinaDepartment of Pain Management, Shengjing Hospital of China Medical University, Shenyang, ChinaDepartment of Anesthesiology, Shengjing Hospital of China Medical University, Shenyang, ChinaObjectivesTrigeminal postherpetic neuralgia (TPHN) often presents with moderate to severe pain, hyperalgesia, and allodynia. Conventional analgesic treatments are poorly effective, which seriously affects the quality of life. This retrospective study aimed to evaluate the efficacy of pulsed radiofrequency (PRF) for the treatment of TPHN.MethodsA total of 90 TPHN patients were selected between January 2014 and December 2016 in the Department of Pain Management, Shengjing Hospital, China Medical University. Patients were randomly divided into two groups according to the order of enrollment (n = 45 per group): group A, peripheral nerve (supraorbital nerve, infraorbital nerve and mental nerve) PRF; group B, gasserian ganglion PRF. Follow-up assessments of visual analogue scale (VAS) pain assessment, SF-36 health status questionnaire, total efficiency rate, and drug dosage of anticonvulsants and opioid analgesics were performed at time points of 1 week, 1 month, 3 months, 6 months, and 1 year after surgery.ResultsAt each postsurgery time point, the VAS decreased, SF-36 (physical and mental components) increased, and drug dosage of anticonvulsants and opioids analgesics decreased in both treatment groups; values at each time point were significantly different from presurgery values (P < 0.05). Compared with group A, VAS decreased, SF-36 increased, and dosage of anticonvulsants and opioids analgesics decreased significantly in group B (P < 0.05). The total efficiency rates one year after surgery in group A and group B were 68.9 and 86.7%, respectively. The total efficiency rate of group B was statistically higher than that of group A (P < 0.05).ConclusionPRF relieved TPHN, and gasserian ganglion PRF was more effective than peripheral nerve PRF. The method was effective and improved the quality of life of the patients. PRF is recommended as a treatment for TPHN.https://www.frontiersin.org/article/10.3389/fnins.2019.00708/fulltrigeminal postherpetic neuralgiapulsed radiofrequencytrigeminal gasserian ganglionperipheral nervesupraorbital nerveinfraorbital nerve |
| spellingShingle | Yuanyuan Ding Tao Hong Hongxi Li Peng Yao Guangyi Zhao Efficacy of CT Guided Pulsed Radiofrequency Treatment for Trigeminal Postherpetic Neuralgia Frontiers in Neuroscience trigeminal postherpetic neuralgia pulsed radiofrequency trigeminal gasserian ganglion peripheral nerve supraorbital nerve infraorbital nerve |
| title | Efficacy of CT Guided Pulsed Radiofrequency Treatment for Trigeminal Postherpetic Neuralgia |
| title_full | Efficacy of CT Guided Pulsed Radiofrequency Treatment for Trigeminal Postherpetic Neuralgia |
| title_fullStr | Efficacy of CT Guided Pulsed Radiofrequency Treatment for Trigeminal Postherpetic Neuralgia |
| title_full_unstemmed | Efficacy of CT Guided Pulsed Radiofrequency Treatment for Trigeminal Postherpetic Neuralgia |
| title_short | Efficacy of CT Guided Pulsed Radiofrequency Treatment for Trigeminal Postherpetic Neuralgia |
| title_sort | efficacy of ct guided pulsed radiofrequency treatment for trigeminal postherpetic neuralgia |
| topic | trigeminal postherpetic neuralgia pulsed radiofrequency trigeminal gasserian ganglion peripheral nerve supraorbital nerve infraorbital nerve |
| url | https://www.frontiersin.org/article/10.3389/fnins.2019.00708/full |
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