A Silicon Nanomembrane Detector for Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry (MALDI-TOF MS) of Large Proteins

A Silicon Nanomembrane Detector for Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry (MALDI-TOF MS) of Large Proteins

We describe a MALDI-TOF ion detector based on freestanding silicon nanomembrane technology. The detector is tested in a commercial MALDI-TOF mass spectrometer with equimolar mixtures of proteins. The operating principle of the nanomembrane detector is based on phonon-assisted field emission from the...

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Bibliographic Details
Main Authors: Jonghoo Park, Robert H. Blick
Format: Article
Language:English
Published: MDPI AG 2013-10-01
Series:Sensors
Subjects:
silicon nanomembrane
MALDI TOF
mass spectrometry
phonon
ion detector
NEMS
Online Access:http://www.mdpi.com/1424-8220/13/10/13708

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