SOX6: a double-edged sword for Ewing sarcoma

SOX6: a double-edged sword for Ewing sarcoma

Developmental pathways play an important role in cancer. We have recently demonstrated that the constitutive activation of the developmental transcription factor SOX6 via the fusion oncoprotein EWSR1-FLI1 (Ewing sarcoma breakpoint region 1 – Friend leukemia virus integration 1) contributes to the ag...

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Bibliographic Details
Main Authors: Aruna Marchetto, Thomas G. P. Grünewald
Format: Article
Language:English
Published: Taylor & Francis Group 2020-09-01
Series:Molecular & Cellular Oncology
Subjects:
sox6
ewing sarcoma
elesclomol
ewsr1-fli1
vulnerability
biomarker
oxidative-stress
Online Access:http://dx.doi.org/10.1080/23723556.2020.1783081

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