Bone Mesenchymal Stem Cell-Derived Extracellular Vesicles Promote Recovery Following Spinal Cord Injury via Improvement of the Integrity of the Blood-Spinal Cord Barrier

Bone Mesenchymal Stem Cell-Derived Extracellular Vesicles Promote Recovery Following Spinal Cord Injury via Improvement of the Integrity of the Blood-Spinal Cord Barrier

Mesenchymal stem cell (MSC) transplantation has been shown to represent a potential treatment for traumatic spinal cord injury (SCI). However, there are several obstacles that need to be overcome before MSCs can be considered for clinical application, such as failure of MSCs to reach the spinal cord...

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Bibliographic Details
Main Authors: Yanhui Lu, Yan Zhou, Ruiyi Zhang, Lulu Wen, Kaimin Wu, Yanfei Li, Yaobing Yao, Ranran Duan, Yanjie Jia
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Neuroscience
Subjects:
extracellular vesicles
bone mesenchymal stromal cells
spinal cord injury
blood spinal cord barrier
pericytes
migration
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2019.00209/full

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