The SGK1 Kinase Inhibitor SI113 Sensitizes Theranostic Effects of the 64CuCl2 in Human Glioblastoma Multiforme Cells

The SGK1 Kinase Inhibitor SI113 Sensitizes Theranostic Effects of the 64CuCl2 in Human Glioblastoma Multiforme Cells

Background/Aims: The importance of copper in the metabolism of cancer cells has been widely studied in the last 20 years and a clear-cut association between copper levels and cancer deregulation has been established. Copper-64, emitting positrons and β-radiations, is indicated for the labeling of a...

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Main Authors: Giada Catalogna, Cristina Talarico, Vincenzo Dattilo, Vincenzo Gangemi, Ferdinando Calabria, Lucia D’Antona, Silvia Schenone, Francesca Musumeci, Cataldo Bianco, Nicola Perrotti, Rosario Amato, Giuseppe L. Cascini
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2017-08-01
Series:Cellular Physiology and Biochemistry
Subjects:
SGK1
GBM
64CuCl2
SI113
Online Access:http://www.karger.com/Article/FullText/480328

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