Alterations of macular ganglion cell complex thickness in obstructive appea

AIM: To observe the changes of macular ganglion cell complex(GCC)thickness in patients with obstructive sleep apnea(OSA)and discuss the relativity between thickness of GCC and OSA.METHODS: Fifty-eight patients with OSA whose Apnea-Hypopnea Index ≥5 and fifty healthy people whose Apnea-Hypopnea Index...

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Main Authors: Jing Yang, Xin Dai, Qing Wang, Hai-Jun Wu
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2021-02-01
Series:Guoji Yanke Zazhi
Subjects:
Online Access:http://ies.ijo.cn/cn_publish/2021/2/202102036.pdf
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author Jing Yang
Xin Dai
Qing Wang
Hai-Jun Wu
author_facet Jing Yang
Xin Dai
Qing Wang
Hai-Jun Wu
author_sort Jing Yang
collection DOAJ
description AIM: To observe the changes of macular ganglion cell complex(GCC)thickness in patients with obstructive sleep apnea(OSA)and discuss the relativity between thickness of GCC and OSA.METHODS: Fifty-eight patients with OSA whose Apnea-Hypopnea Index ≥5 and fifty healthy people whose Apnea-Hypopnea Index <5 were enrolled in this study. OSA patients were further divided into mild, moderate, and severe OSA groups according to their Apnea-Hypopnea Inde. RTVUE 100-2 optical coherence tomography was used to measure the GCC thickness. The examination included average thickness of GCC(GCC-Avg), superior(GCC-Sup)and inferior thickness of GCC(GCC-Inf), focal loss of volume(FLV)and general loss of volume(GLV). The difference in GCC thickness was analyzed among four groups. RESULTS: The thickness of GCC of the OSA groups was thinner than that of the normal control group(P<0.05), and FLV in the OSA groups was higher than that in the normal control group(P<0.05), but there was no significant difference in FLV between OSA groups(P>0.05). GLV increased in the OSA groups compared with the control group.CONCLUSION:The macular GCC thickness decreased in OSA patients, and the thickness of GCC decreased with the increase of OSA patients' severity(AHI).
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spelling doaj.art-3cf71cac96cb4354a2443fc719f5857b2022-12-21T20:00:57ZengPress of International Journal of Ophthalmology (IJO PRESS)Guoji Yanke Zazhi1672-51232021-02-0121236436710.3980/j.issn.1672-5123.2021.2.36202102036Alterations of macular ganglion cell complex thickness in obstructive appeaJing Yang0Xin Dai1Qing Wang2Hai-Jun Wu3Department of Ophthalmology and Optometry, Heze Medical College, Heze 274000, Shandong Province, ChinaDepartment of Ophthalmology and Optometry, Heze Medical College, Heze 274000, Shandong Province, ChinaDepartment of Ophthalmology and Optometry, Heze Medical College, Heze 274000, Shandong Province, ChinaDepartment of Ophthalmology, Heze Municipal Hospital, Heze 274000, Shandong Province, ChinaAIM: To observe the changes of macular ganglion cell complex(GCC)thickness in patients with obstructive sleep apnea(OSA)and discuss the relativity between thickness of GCC and OSA.METHODS: Fifty-eight patients with OSA whose Apnea-Hypopnea Index ≥5 and fifty healthy people whose Apnea-Hypopnea Index <5 were enrolled in this study. OSA patients were further divided into mild, moderate, and severe OSA groups according to their Apnea-Hypopnea Inde. RTVUE 100-2 optical coherence tomography was used to measure the GCC thickness. The examination included average thickness of GCC(GCC-Avg), superior(GCC-Sup)and inferior thickness of GCC(GCC-Inf), focal loss of volume(FLV)and general loss of volume(GLV). The difference in GCC thickness was analyzed among four groups. RESULTS: The thickness of GCC of the OSA groups was thinner than that of the normal control group(P<0.05), and FLV in the OSA groups was higher than that in the normal control group(P<0.05), but there was no significant difference in FLV between OSA groups(P>0.05). GLV increased in the OSA groups compared with the control group.CONCLUSION:The macular GCC thickness decreased in OSA patients, and the thickness of GCC decreased with the increase of OSA patients' severity(AHI).http://ies.ijo.cn/cn_publish/2021/2/202102036.pdfganglion cell complexoptical coherence tomographyobstructive sleep apnea
spellingShingle Jing Yang
Xin Dai
Qing Wang
Hai-Jun Wu
Alterations of macular ganglion cell complex thickness in obstructive appea
Guoji Yanke Zazhi
ganglion cell complex
optical coherence tomography
obstructive sleep apnea
title Alterations of macular ganglion cell complex thickness in obstructive appea
title_full Alterations of macular ganglion cell complex thickness in obstructive appea
title_fullStr Alterations of macular ganglion cell complex thickness in obstructive appea
title_full_unstemmed Alterations of macular ganglion cell complex thickness in obstructive appea
title_short Alterations of macular ganglion cell complex thickness in obstructive appea
title_sort alterations of macular ganglion cell complex thickness in obstructive appea
topic ganglion cell complex
optical coherence tomography
obstructive sleep apnea
url http://ies.ijo.cn/cn_publish/2021/2/202102036.pdf
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