Regulatory CD4+Foxp3+ T cells control the severity of anaphylaxis.

Regulatory CD4+Foxp3+ T cells control the severity of anaphylaxis.

OBJECTIVE: Anaphylaxis is a life-threatening outcome of immediate-type hypersensitivity to allergen, consecutive to mast cell degranulation by allergen-specific IgE. Regulatory T cells (Treg) can control allergic sensitization and mast cell degranulation, yet their clinical benefit on anaphylactic s...

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Bibliographic Details
Main Authors: Reem Kanjarawi, Michel Dy, Emilie Bardel, Tim Sparwasser, Bertrand Dubois, Salah Mecheri, Dominique Kaiserlian
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3724852?pdf=render

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