Does muscle strength predict working memory? A cross-sectional fNIRS study in older adults
ObjectivePrevious research has primarily focused on the association between muscle strength and global cognitive function in older adults, while the connection between muscle strength and advanced cognitive function such as inhibition and working memory (WM) remains unclear. This study aimed to inve...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-10-01
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| Series: | Frontiers in Aging Neuroscience |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fnagi.2023.1243283/full |
| _version_ | 1797663328540033024 |
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| author | Zhidong Cai Zhidong Cai Xing Wang Qiang Wang |
| author_facet | Zhidong Cai Zhidong Cai Xing Wang Qiang Wang |
| author_sort | Zhidong Cai |
| collection | DOAJ |
| description | ObjectivePrevious research has primarily focused on the association between muscle strength and global cognitive function in older adults, while the connection between muscle strength and advanced cognitive function such as inhibition and working memory (WM) remains unclear. This study aimed to investigate the relationship among muscle strength, WM, and task-related cortex hemodynamics.MethodsWe recruited eighty-one older adults. Muscle strength was measured using a grip and lower limb strength protocol. We measured the WM performance by using reaction time (RT) and accuracy (ACC) in the N-back task and the cortical hemodynamics of the prefrontal cortex (PFC) by functional near-infrared spectroscopy (fNIRS).ResultsWe found positive correlations between grip strength (p < 0.05), 30-s sit-up (p < 0.05) and ACC, negative correlation between grip strength (p < 0.05) and RT. Furthermore, we observed positive correlations between grip strength and the level of oxygenated hemoglobin (HbO2) in dorsolateral prefrontal cortex, frontopolar area, ventrolateral prefrontal cortex (p < 0.05), and negative correlations between grip strength and the level of deoxygenated hemoglobin (Hb) in left dorsolateral prefrontal cortex, frontopolar area, left ventrolateral prefrontal cortex (p < 0.05). Additionally, we noticed positive correlations between RT and the level of Hb in left dorsolateral prefrontal cortex, right frontopolar area (p < 0.05), and negative correlations between RT and the level of HbO2 in left dorsolateral prefrontal cortex, frontopolar area (p < 0.05). However, the cortical hemodynamics did not mediate the relationship between muscle strength and WM performance (RT, ACC).ConclusionThe grip strength of older adults predicted WM in the cross-section study. The level of hemodynamics in PFC can serve as a predictor of WM. |
| first_indexed | 2024-03-11T19:12:55Z |
| format | Article |
| id | doaj.art-3cfc06ba88de4f15941053209b757438 |
| institution | Directory Open Access Journal |
| issn | 1663-4365 |
| language | English |
| last_indexed | 2024-03-11T19:12:55Z |
| publishDate | 2023-10-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Aging Neuroscience |
| spelling | doaj.art-3cfc06ba88de4f15941053209b7574382023-10-09T09:13:35ZengFrontiers Media S.A.Frontiers in Aging Neuroscience1663-43652023-10-011510.3389/fnagi.2023.12432831243283Does muscle strength predict working memory? A cross-sectional fNIRS study in older adultsZhidong Cai0Zhidong Cai1Xing Wang2Qiang Wang3Department of Physical Education, Suzhou University of Science and Technology, Suzhou, ChinaSchool of Physical Education, Shanghai University of Sport, Shanghai, ChinaSchool of Physical Education, Shanghai University of Sport, Shanghai, ChinaSchool of Physical Education, Guangzhou Sport University, Guangzhou, ChinaObjectivePrevious research has primarily focused on the association between muscle strength and global cognitive function in older adults, while the connection between muscle strength and advanced cognitive function such as inhibition and working memory (WM) remains unclear. This study aimed to investigate the relationship among muscle strength, WM, and task-related cortex hemodynamics.MethodsWe recruited eighty-one older adults. Muscle strength was measured using a grip and lower limb strength protocol. We measured the WM performance by using reaction time (RT) and accuracy (ACC) in the N-back task and the cortical hemodynamics of the prefrontal cortex (PFC) by functional near-infrared spectroscopy (fNIRS).ResultsWe found positive correlations between grip strength (p < 0.05), 30-s sit-up (p < 0.05) and ACC, negative correlation between grip strength (p < 0.05) and RT. Furthermore, we observed positive correlations between grip strength and the level of oxygenated hemoglobin (HbO2) in dorsolateral prefrontal cortex, frontopolar area, ventrolateral prefrontal cortex (p < 0.05), and negative correlations between grip strength and the level of deoxygenated hemoglobin (Hb) in left dorsolateral prefrontal cortex, frontopolar area, left ventrolateral prefrontal cortex (p < 0.05). Additionally, we noticed positive correlations between RT and the level of Hb in left dorsolateral prefrontal cortex, right frontopolar area (p < 0.05), and negative correlations between RT and the level of HbO2 in left dorsolateral prefrontal cortex, frontopolar area (p < 0.05). However, the cortical hemodynamics did not mediate the relationship between muscle strength and WM performance (RT, ACC).ConclusionThe grip strength of older adults predicted WM in the cross-section study. The level of hemodynamics in PFC can serve as a predictor of WM.https://www.frontiersin.org/articles/10.3389/fnagi.2023.1243283/fullcognitionmuscle strength30-s sit-upgrip strengthN-backfunctional near infrared spectroscopy |
| spellingShingle | Zhidong Cai Zhidong Cai Xing Wang Qiang Wang Does muscle strength predict working memory? A cross-sectional fNIRS study in older adults Frontiers in Aging Neuroscience cognition muscle strength 30-s sit-up grip strength N-back functional near infrared spectroscopy |
| title | Does muscle strength predict working memory? A cross-sectional fNIRS study in older adults |
| title_full | Does muscle strength predict working memory? A cross-sectional fNIRS study in older adults |
| title_fullStr | Does muscle strength predict working memory? A cross-sectional fNIRS study in older adults |
| title_full_unstemmed | Does muscle strength predict working memory? A cross-sectional fNIRS study in older adults |
| title_short | Does muscle strength predict working memory? A cross-sectional fNIRS study in older adults |
| title_sort | does muscle strength predict working memory a cross sectional fnirs study in older adults |
| topic | cognition muscle strength 30-s sit-up grip strength N-back functional near infrared spectroscopy |
| url | https://www.frontiersin.org/articles/10.3389/fnagi.2023.1243283/full |
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