Kyrle′s disease presenting in an extensive distribution along lines of Blaschko
A 24-year-old lady presented with the complaints of asymptomatic dark, raised lesions over her body since past 4 years. Dermatological examination revealed hyperkeratotic, hyperpigmented papules in a Blaschkoid distribution over trunk and extremities. The hyperkeratotic lesions could be removed leav...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2015-01-01
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| Series: | Indian Journal of Dermatology |
| Subjects: | |
| Online Access: | http://www.e-ijd.org/article.asp?issn=0019-5154;year=2015;volume=60;issue=4;spage=423;epage=423;aulast=Verma |
| _version_ | 1819141475455205376 |
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| author | Rajesh Verma Biju Vasudevan Sunita Kakkar Pratibha Mishra Vijendran Pragasam Disha Dabbas |
| author_facet | Rajesh Verma Biju Vasudevan Sunita Kakkar Pratibha Mishra Vijendran Pragasam Disha Dabbas |
| author_sort | Rajesh Verma |
| collection | DOAJ |
| description | A 24-year-old lady presented with the complaints of asymptomatic dark, raised lesions over her body since past 4 years. Dermatological examination revealed hyperkeratotic, hyperpigmented papules in a Blaschkoid distribution over trunk and extremities. The hyperkeratotic lesions could be removed leaving behind a small crater. Skin biopsy revealed hyperkeratosis, parakeratosis with epidermal invagination, focal cornified plug with basophilic degenerated material and dyskeratotic keratinocytes. Dermis showed dilated capillaries with moderate amount of perivascular lymphocytic infiltrate and granulomatous lymphocytic infiltrate in the deep dermis. A diagnosis of Kyrle′s disease was made and patient was started on oral acitretin 25 mg daily with satisfactory response to therapy. This is the first reported instance of Kyrle′s disease occurring in an extensive Blaschkoid distribution. |
| first_indexed | 2024-12-22T11:55:03Z |
| format | Article |
| id | doaj.art-3d00ee1c5071418f9e226aa9bdade8b9 |
| institution | Directory Open Access Journal |
| issn | 0019-5154 1998-3611 |
| language | English |
| last_indexed | 2024-12-22T11:55:03Z |
| publishDate | 2015-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Dermatology |
| spelling | doaj.art-3d00ee1c5071418f9e226aa9bdade8b92022-12-21T18:26:51ZengWolters Kluwer Medknow PublicationsIndian Journal of Dermatology0019-51541998-36112015-01-0160442342310.4103/0019-5154.160542Kyrle′s disease presenting in an extensive distribution along lines of BlaschkoRajesh VermaBiju VasudevanSunita KakkarPratibha MishraVijendran PragasamDisha DabbasA 24-year-old lady presented with the complaints of asymptomatic dark, raised lesions over her body since past 4 years. Dermatological examination revealed hyperkeratotic, hyperpigmented papules in a Blaschkoid distribution over trunk and extremities. The hyperkeratotic lesions could be removed leaving behind a small crater. Skin biopsy revealed hyperkeratosis, parakeratosis with epidermal invagination, focal cornified plug with basophilic degenerated material and dyskeratotic keratinocytes. Dermis showed dilated capillaries with moderate amount of perivascular lymphocytic infiltrate and granulomatous lymphocytic infiltrate in the deep dermis. A diagnosis of Kyrle′s disease was made and patient was started on oral acitretin 25 mg daily with satisfactory response to therapy. This is the first reported instance of Kyrle′s disease occurring in an extensive Blaschkoid distribution.http://www.e-ijd.org/article.asp?issn=0019-5154;year=2015;volume=60;issue=4;spage=423;epage=423;aulast=VermaBlaschkoidKyrle′s diseaseperforating disordersretinoids |
| spellingShingle | Rajesh Verma Biju Vasudevan Sunita Kakkar Pratibha Mishra Vijendran Pragasam Disha Dabbas Kyrle′s disease presenting in an extensive distribution along lines of Blaschko Indian Journal of Dermatology Blaschkoid Kyrle′s disease perforating disorders retinoids |
| title | Kyrle′s disease presenting in an extensive distribution along lines of Blaschko |
| title_full | Kyrle′s disease presenting in an extensive distribution along lines of Blaschko |
| title_fullStr | Kyrle′s disease presenting in an extensive distribution along lines of Blaschko |
| title_full_unstemmed | Kyrle′s disease presenting in an extensive distribution along lines of Blaschko |
| title_short | Kyrle′s disease presenting in an extensive distribution along lines of Blaschko |
| title_sort | kyrle s disease presenting in an extensive distribution along lines of blaschko |
| topic | Blaschkoid Kyrle′s disease perforating disorders retinoids |
| url | http://www.e-ijd.org/article.asp?issn=0019-5154;year=2015;volume=60;issue=4;spage=423;epage=423;aulast=Verma |
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