Limosilactobacillus reuteri ID-D01 improves exercise performance and reduces muscle fatigue in C57BL/6 mice through regulation of oxidative capacity
The objective of this study was to evaluate the influence of the Limosilactobacillus reuteri ID-D01 (ID-D01) lactic acid bacteria probiotic on exercise performance and muscle fatigue in C57BL/6 mice. ID-D01 improved exercise endurance by extending treadmill running time and forced swimming duration....
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2024-05-01
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| Series: | Journal of Functional Foods |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1756464624001270 |
| _version_ | 1797257668743659520 |
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| author | Han Sol Choi Ye-Ji Jang Ikhoon Oh Jae Hyuk Chung Jin Seok Moon |
| author_facet | Han Sol Choi Ye-Ji Jang Ikhoon Oh Jae Hyuk Chung Jin Seok Moon |
| author_sort | Han Sol Choi |
| collection | DOAJ |
| description | The objective of this study was to evaluate the influence of the Limosilactobacillus reuteri ID-D01 (ID-D01) lactic acid bacteria probiotic on exercise performance and muscle fatigue in C57BL/6 mice. ID-D01 improved exercise endurance by extending treadmill running time and forced swimming duration. Moreover, mice treated with ID-D01 exhibited increased quadriceps muscle tissue weight, suggesting a potential for enhancing muscle growth. Serum analysis showed decreased muscle fatigue markers, and lower levels of lactate, and ammonia, indicating reduced exercise-induced fatigue. ID-D01 also affected intramuscular factors such as citrate synthase and glycogen. Notably, citrate synthase levels increased, indicating improved aerobic capacity, while intramuscular glycogen decreased. ID-D01 decreased reactive oxygen species and increased antioxidant enzymes SOD2 and catalase, in muscle tissue. This study identifies the potential of ID-D01 to improve exercise performance and relieve muscle fatigue. Further, it provides a rationale for the development of ID-D01-based functional supplements for individuals who are physically active. |
| first_indexed | 2024-04-24T22:41:18Z |
| format | Article |
| id | doaj.art-3d01f681ded745189865eda453cb7987 |
| institution | Directory Open Access Journal |
| issn | 1756-4646 |
| language | English |
| last_indexed | 2024-04-24T22:41:18Z |
| publishDate | 2024-05-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Functional Foods |
| spelling | doaj.art-3d01f681ded745189865eda453cb79872024-03-19T04:18:21ZengElsevierJournal of Functional Foods1756-46462024-05-01116106125Limosilactobacillus reuteri ID-D01 improves exercise performance and reduces muscle fatigue in C57BL/6 mice through regulation of oxidative capacityHan Sol Choi0Ye-Ji Jang1Ikhoon Oh2Jae Hyuk Chung3Jin Seok Moon4YUNOVIA Co., Ltd., Hwaseong 18449, Republic of KoreaYUNOVIA Co., Ltd., Hwaseong 18449, Republic of KoreaYUNOVIA Co., Ltd., Hwaseong 18449, Republic of KoreaYUNOVIA Co., Ltd., Hwaseong 18449, Republic of KoreaYUNOVIA Co., Ltd., Hwaseong 18449, Republic of Korea; Ildong Pharmaceutical Co., Ltd., Seoul 06752, Republic of Korea; Corresponding author.The objective of this study was to evaluate the influence of the Limosilactobacillus reuteri ID-D01 (ID-D01) lactic acid bacteria probiotic on exercise performance and muscle fatigue in C57BL/6 mice. ID-D01 improved exercise endurance by extending treadmill running time and forced swimming duration. Moreover, mice treated with ID-D01 exhibited increased quadriceps muscle tissue weight, suggesting a potential for enhancing muscle growth. Serum analysis showed decreased muscle fatigue markers, and lower levels of lactate, and ammonia, indicating reduced exercise-induced fatigue. ID-D01 also affected intramuscular factors such as citrate synthase and glycogen. Notably, citrate synthase levels increased, indicating improved aerobic capacity, while intramuscular glycogen decreased. ID-D01 decreased reactive oxygen species and increased antioxidant enzymes SOD2 and catalase, in muscle tissue. This study identifies the potential of ID-D01 to improve exercise performance and relieve muscle fatigue. Further, it provides a rationale for the development of ID-D01-based functional supplements for individuals who are physically active.http://www.sciencedirect.com/science/article/pii/S1756464624001270Limosilactobacillus reuteri ID-D01Muscle fatigueAntioxidantExercise performanceProbiotics |
| spellingShingle | Han Sol Choi Ye-Ji Jang Ikhoon Oh Jae Hyuk Chung Jin Seok Moon Limosilactobacillus reuteri ID-D01 improves exercise performance and reduces muscle fatigue in C57BL/6 mice through regulation of oxidative capacity Journal of Functional Foods Limosilactobacillus reuteri ID-D01 Muscle fatigue Antioxidant Exercise performance Probiotics |
| title | Limosilactobacillus reuteri ID-D01 improves exercise performance and reduces muscle fatigue in C57BL/6 mice through regulation of oxidative capacity |
| title_full | Limosilactobacillus reuteri ID-D01 improves exercise performance and reduces muscle fatigue in C57BL/6 mice through regulation of oxidative capacity |
| title_fullStr | Limosilactobacillus reuteri ID-D01 improves exercise performance and reduces muscle fatigue in C57BL/6 mice through regulation of oxidative capacity |
| title_full_unstemmed | Limosilactobacillus reuteri ID-D01 improves exercise performance and reduces muscle fatigue in C57BL/6 mice through regulation of oxidative capacity |
| title_short | Limosilactobacillus reuteri ID-D01 improves exercise performance and reduces muscle fatigue in C57BL/6 mice through regulation of oxidative capacity |
| title_sort | limosilactobacillus reuteri id d01 improves exercise performance and reduces muscle fatigue in c57bl 6 mice through regulation of oxidative capacity |
| topic | Limosilactobacillus reuteri ID-D01 Muscle fatigue Antioxidant Exercise performance Probiotics |
| url | http://www.sciencedirect.com/science/article/pii/S1756464624001270 |
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