Synthetic Applications of Aziridinium Ions
Nonactivated aziridine with an electron-donating group at the ring nitrogen should be activated to an aziridinium ion prior to being converted to cyclic and acyclic nitrogen-containing molecules. This review describes ways to generate aziridinium ions and their utilization for synthetic purposes. Sp...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-03-01
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| Series: | Molecules |
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| Online Access: | https://www.mdpi.com/1420-3049/26/6/1774 |
| _version_ | 1797540481187446784 |
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| author | Jala Ranjith Hyun-Joon Ha |
| author_facet | Jala Ranjith Hyun-Joon Ha |
| author_sort | Jala Ranjith |
| collection | DOAJ |
| description | Nonactivated aziridine with an electron-donating group at the ring nitrogen should be activated to an aziridinium ion prior to being converted to cyclic and acyclic nitrogen-containing molecules. This review describes ways to generate aziridinium ions and their utilization for synthetic purposes. Specifically, the intra- and intermolecular formation of aziridinium ions with proper electrophiles are classified, and their regio- and stereoselective transformations with nucleophiles are described on the basis of recent developments. |
| first_indexed | 2024-03-10T13:00:47Z |
| format | Article |
| id | doaj.art-3d031e039a8c4a46982a4b3d70c40821 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-10T13:00:47Z |
| publishDate | 2021-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-3d031e039a8c4a46982a4b3d70c408212023-11-21T11:29:39ZengMDPI AGMolecules1420-30492021-03-01266177410.3390/molecules26061774Synthetic Applications of Aziridinium IonsJala Ranjith0Hyun-Joon Ha1Department of Chemistry, Hankuk University of Foreign Studies, Yongin 17035, KoreaDepartment of Chemistry, Hankuk University of Foreign Studies, Yongin 17035, KoreaNonactivated aziridine with an electron-donating group at the ring nitrogen should be activated to an aziridinium ion prior to being converted to cyclic and acyclic nitrogen-containing molecules. This review describes ways to generate aziridinium ions and their utilization for synthetic purposes. Specifically, the intra- and intermolecular formation of aziridinium ions with proper electrophiles are classified, and their regio- and stereoselective transformations with nucleophiles are described on the basis of recent developments.https://www.mdpi.com/1420-3049/26/6/1774aziridinenonactivated aziridineaziridinium ionring-openingsynthesisnitrogen-containing molecules |
| spellingShingle | Jala Ranjith Hyun-Joon Ha Synthetic Applications of Aziridinium Ions Molecules aziridine nonactivated aziridine aziridinium ion ring-opening synthesis nitrogen-containing molecules |
| title | Synthetic Applications of Aziridinium Ions |
| title_full | Synthetic Applications of Aziridinium Ions |
| title_fullStr | Synthetic Applications of Aziridinium Ions |
| title_full_unstemmed | Synthetic Applications of Aziridinium Ions |
| title_short | Synthetic Applications of Aziridinium Ions |
| title_sort | synthetic applications of aziridinium ions |
| topic | aziridine nonactivated aziridine aziridinium ion ring-opening synthesis nitrogen-containing molecules |
| url | https://www.mdpi.com/1420-3049/26/6/1774 |
| work_keys_str_mv | AT jalaranjith syntheticapplicationsofaziridiniumions AT hyunjoonha syntheticapplicationsofaziridiniumions |