T cell migration and effector function differences in familial adenomatous polyposis patients with APC gene mutations

T cell migration and effector function differences in familial adenomatous polyposis patients with APC gene mutations

Familial adenomatous polyposis (FAP) is an inherited disease characterized by the development of large number of colorectal adenomas with high risk of evolving into colorectal tumors. Mutations of the Adenomatous polyposis coli (APC) gene is often at the origin of this disease, as well as of a high...

Full description

Bibliographic Details
Main Authors: Céline Cuche, Marta Mastrogiovanni, Marie Juzans, Hélène Laude, Marie-Noëlle Ungeheuer, Daniel Krentzel, Maria Isabella Gariboldi, Daniel Scott-Algara, Marianne Madec, Sophie Goyard, Camille Floch, Gaëlle Chauveau-Le Friec, Pierre Lafaye, Charlotte Renaudat, Muriel Le Bidan, Christine Micallef, Sandrine Schmutz, Sébastien Mella, Sophie Novault, Milena Hasan, Darragh Duffy, Vincenzo Di Bartolo, Andrés Alcover
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Immunology
Subjects:
Adenomatous polyposis coli
APC
familial adenomatous polyposis
T cell activation
T cell migration
cytokines
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1163466/full

Similar Items

Similar Items