Host Synthesized Carbohydrate Antigens on Viral Glycoproteins as “Achilles’ Heel” of Viruses Contributing to Anti-Viral Immune Protection

Host Synthesized Carbohydrate Antigens on Viral Glycoproteins as “Achilles’ Heel” of Viruses Contributing to Anti-Viral Immune Protection

The glycans on enveloped viruses are synthesized by host-cell machinery. Some of these glycans on zoonotic viruses of mammalian reservoirs are recognized by human natural antibodies that may protect against such viruses. These antibodies are produced mostly against carbohydrate antigens on gastroint...

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Bibliographic Details
Main Author:	Uri Galili
Format:	Article
Language:	English
Published:	MDPI AG 2020-09-01
Series:	International Journal of Molecular Sciences
Subjects:	zoonotic virus viral epidemics glycan shield <i>α</i>-gal epitopes anti-Gal Neu5Gc
Online Access:	https://www.mdpi.com/1422-0067/21/18/6702

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