Parkin inhibits proliferation and migration of bladder cancer via ubiquitinating Catalase

Parkin inhibits proliferation and migration of bladder cancer via ubiquitinating Catalase

Abstract PRKN is a key gene involved in mitophagy in Parkinson’s disease. However, recent studies have demonstrated that it also plays a role in the development and metastasis of several types of cancers, both in a mitophagy-dependent and mitophagy-independent manner. Despite this, the potential eff...

Full description

Bibliographic Details
Main Authors:	Renjie Zhang, Wenyu Jiang, Gang Wang, Yi Zhang, Wei Liu, Mingxing Li, Jingtian Yu, Xin Yan, Fenfang Zhou, Wenzhi Du, Kaiyu Qian, Yu Xiao, Tongzu Liu, Lingao Ju, Xinghuan Wang
Format:	Article
Language:	English
Published:	Nature Portfolio 2024-02-01
Series:	Communications Biology
Online Access:	https://doi.org/10.1038/s42003-024-05935-x

Similar Items

DNA polymerase POLD1 promotes proliferation and metastasis of bladder cancer by stabilizing MYC
by: Yejinpeng Wang, et al.
Published: (2023-04-01)

USP43 stabilizes c-Myc to promote glycolysis and metastasis in bladder cancer
by: Mingxing Li, et al.
Published: (2024-01-01)

Pectolinarigenin inhibits bladder urothelial carcinoma cell proliferation by regulating DNA damage/autophagy pathways
by: Zhao Deng, et al.
Published: (2023-07-01)

Melatonin inhibits bladder tumorigenesis by suppressing PPARγ/ENO1-mediated glycolysis
by: Dexin Shen, et al.
Published: (2023-04-01)

Parkin-mediated ubiquitination inhibits BAK apoptotic activity by blocking its canonical hydrophobic groove
by: Peng Cheng, et al.
Published: (2023-12-01)

Parkin regulates IGF2BP3 through ubiquitination in the tumourigenesis of cervical cancer
by: Xin Sun, et al.
Published: (2023-10-01)

Parkin-mediated ubiquitination contributes to the constitutive turnover of mitochondrial fission factor (Mff)
by: Lee, L, et al.
Published: (2019)

Parkin-mediated ubiquitination contributes to the constitutive turnover of mitochondrial fission factor (Mff).
by: Laura Lee, et al.
Published: (2019-01-01)

Genetically supported causality between benign prostate hyperplasia and urinary bladder neoplasms: A mendelian randomization study
by: Wenzhi Du, et al.
Published: (2022-11-01)

High-content phenotypic screen to identify small molecule enhancers of Parkin-dependent ubiquitination and mitophagy
by: Roberta Tufi, et al.
Published: (2023-04-01)

Correction: Qian et al. Capsaicin Suppresses Cell Proliferation, Induces Cell Cycle Arrest and ROS Production in Bladder Cancer Cells through FOXO3a-Mediated Pathways. <i>Molecules</i> 2016, <i>21</i>, 1406
by: Kaiyu Qian, et al.
Published: (2022-10-01)

LncRNA SNHG1 Facilitates Tumor Proliferation and Represses Apoptosis by Regulating PPARγ Ubiquitination in Bladder Cancer
by: Hongzhou Cai, et al.
Published: (2022-09-01)

UCHL5 Promotes Proliferation and Migration of Bladder Cancer Cells by Activating c-Myc via AKT/mTOR Signaling
by: Yuanfei Cao, et al.
Published: (2022-11-01)

Selective localization of Mfn2 near PINK1 enables its preferential ubiquitination by Parkin on mitochondria
by: Marta Vranas, et al.
Published: (2022-01-01)

Regulation of Parkin in Cr (VI)-induced mitophagy in chicken hepatocytes
by: Lumei Wang, et al.
Published: (2022-12-01)

The role of E3 ubiquitin ligases and deubiquitinases in bladder cancer development and immunotherapy
by: Xuemei Wang, et al.
Published: (2023-05-01)

Molecular mechanism of WWP1‐mediated ubiquitination modification affecting proliferation and invasion/migration of liver cancer cells
by: Chao Zhang, et al.
Published: (2024-03-01)

E3 ubiquitin ligases and deubiquitinases in bladder cancer tumorigenesis and implications for immunotherapies
by: Maoyu Wang, et al.
Published: (2023-07-01)

Parkin the bus to manage stress
by: Amandeep Kaur, et al.
Published: (2019-08-01)

Parkin beyond Parkinson’s Disease—A Functional Meaning of Parkin Downregulation in TDP-43 Proteinopathies
by: Katarzyna Gaweda-Walerych, et al.
Published: (2021-12-01)

PRMT7 inhibits proliferation and migration of bladder cancer cells by regulating Notch signaling pathway
by: WANG Xuemei, CHENG Yu, QI Jiemin
Published: (2023-05-01)

Histone methyltransferase SETD2: An epigenetic driver in clear cell renal cell carcinoma
by: Mengxue Yu, et al.
Published: (2023-03-01)

Hepatoid adenocarcinoma in ureter with next-generation sequencing: A case report and literature review
by: Mengxin Lu, et al.
Published: (2024-01-01)

Siglec-15 regulates cell proliferation, migration and invasion in bladder cancer
by: Han-Yuan Gao, et al.
Published: (2024-04-01)

Friend or Foe? The Roles of Antioxidants in Acute Lung Injury
by: Yang Liu, et al.
Published: (2021-12-01)

Cathepsin K promotes the proliferation of hepatocellular carcinoma cells through induction of SIAH1 ubiquitination and degradation
by: Chengming Zhang, et al.
Published: (2023-06-01)

Parkin disease: a clinicopathologic entity?
by: Doherty, K, et al.
Published: (2013)

A mutational atlas for Parkin proteostasis
by: Lene Clausen, et al.
Published: (2024-02-01)

RNF112-mediated FOXM1 ubiquitination suppresses the proliferation and invasion of gastric cancer
by: Shengwei Zhang, et al.
Published: (2023-06-01)

Monofunctional Heme-Catalases
by: Wilhelm Hansberg
Published: (2022-11-01)

Mitoquinone alleviates osteoarthritis progress by activating the NRF2-Parkin axis
by: Liangcai Hou, et al.
Published: (2024-02-01)

Mitoquinone alleviates osteoarthritis progress by activating the NRF2-Parkin axis
by: Liangcai Hou, et al.
Published: (2023-09-01)

E3 ubiquitin ligase RNF180 prevents excessive PCDH10 methylation to suppress the proliferation and metastasis of gastric cancer cells by promoting ubiquitination of DNMT1
by: Nannan Zhang, et al.
Published: (2023-05-01)

Estradiol cypionate inhibits proliferation and promotes apoptosis of gastric cancer by regulating AKT ubiquitination
by: Xiaochen Qiu, et al.
Published: (2023-09-01)

Ubiquitin-specific protease 14 targets PFKL-mediated glycolysis to promote the proliferation and migration of oral squamous cell carcinoma
by: Xingming Zhang, et al.
Published: (2024-02-01)

Atypical presentations of UTUC: a case report of three patients
by: Linfa Guo, et al.
Published: (2024-01-01)

RNAi-Mediated Silencing of Catalase Gene Promotes Apoptosis and Impairs Proliferation of Bovine Granulosa Cells under Heat Stress
by: Adnan Khan, et al.
Published: (2020-06-01)

Hsp70-Bim interaction facilitates mitophagy by recruiting parkin and TOMM20 into a complex
by: Ting Song, et al.
Published: (2023-05-01)

POU5F1 promotes the proliferation, migration, and invasion of gastric cancer cells by reducing the ubiquitination level of TRAF6
by: Wenshuo Yang, et al.
Published: (2023-12-01)

Comparison of Thulium Fiber Laser versus Holmium laser in ureteroscopic lithotripsy: a Meta-analysis and systematic review
by: Xiaoyu Tang, et al.
Published: (2024-02-01)