Esophagectomy in Elderly Patients With Esophageal Cancer
Background: The number of elderly patients who undergo surgery for esophageal cancer is increasing as a result of longer life expectancy, but little is known about the morbidity and outcome of such procedures in the elderly. This study compared the results of surgery for evaluating the effect of age...
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| Format: | Article |
| Language: | English |
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Taiwan Society of Geriatric Emergency and Critical Medicine (TSGECM)
2010-12-01
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| Series: | International Journal of Gerontology |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1873959810000086 |
| _version_ | 1818571610371653632 |
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| author | Hung-Chang Liu Yi-Ching Chen Chih-Hao Chen Yu-Jen Chen |
| author_facet | Hung-Chang Liu Yi-Ching Chen Chih-Hao Chen Yu-Jen Chen |
| author_sort | Hung-Chang Liu |
| collection | DOAJ |
| description | Background: The number of elderly patients who undergo surgery for esophageal cancer is increasing as a result of longer life expectancy, but little is known about the morbidity and outcome of such procedures in the elderly. This study compared the results of surgery for evaluating the effect of age on esophageal cancer patients.
Methods: Patients who underwent surgery with curative intent for esophageal cancer from January 1999 to July 2009 were included in this retrospective study. Data were compared between patients ≥70 years (elderly group) and patients <70 years old (younger group). Patient characteristics, hospital course, surgical mortality, morbidity, and survival were compared between patients in these two age groups.
Results: Of the 166 patients included, 35 (21.1%) were at least 70 years old (mean age, 75.2 years) and 131 (78.9%) were younger than 70 years old (mean age, 51.8 years). All 29 eligible elderly and 29 randomly selected, age-adjusted younger patients were included for a balanced comparison. The elderly group had significantly longer hospital stays (46 vs. 22 days) and a significantly higher incidence of surgical morbidity (51.7% vs. 20.7%). Cardiopulmonary-related complications were the main causes of operative morbidity in the elderly group. The elderly group also had higher performance state scores. On the basis of less adjuvant anticancer treatment received, the overall survival of elderly patients was comparable to their younger counterparts (12.1 vs. 12.7 months; p = 0.77).
Conclusion: The results of this study suggest that curative surgery for esophageal cancer in elderly patients may result in comparable overall survival and greater, but acceptable, morbidity in comparison with younger patients. Our data suggest that age ≥70 years old should not be considered a counterindicator for curative surgery in esophageal cancer patients. |
| first_indexed | 2024-12-14T13:58:19Z |
| format | Article |
| id | doaj.art-3d10781d87d1451e9aeafce5cccdc52f |
| institution | Directory Open Access Journal |
| issn | 1873-9598 |
| language | English |
| last_indexed | 2024-12-14T13:58:19Z |
| publishDate | 2010-12-01 |
| publisher | Taiwan Society of Geriatric Emergency and Critical Medicine (TSGECM) |
| record_format | Article |
| series | International Journal of Gerontology |
| spelling | doaj.art-3d10781d87d1451e9aeafce5cccdc52f2022-12-21T22:58:46ZengTaiwan Society of Geriatric Emergency and Critical Medicine (TSGECM)International Journal of Gerontology1873-95982010-12-014417617910.1016/j.ijge.2010.11.003Esophagectomy in Elderly Patients With Esophageal CancerHung-Chang Liu0Yi-Ching Chen1Chih-Hao Chen2Yu-Jen Chen3Division of Thoracic Surgery, Department of Surgery, Mackay Memorial Hospital, Taipei, TaiwanDivision of Thoracic Surgery, Department of Surgery, Mackay Memorial Hospital, Taipei, TaiwanDivision of Thoracic Surgery, Department of Surgery, Mackay Memorial Hospital, Taipei, TaiwanDepartment of Radiation Oncology, Mackay Memorial Hospital, Taipei, TaiwanBackground: The number of elderly patients who undergo surgery for esophageal cancer is increasing as a result of longer life expectancy, but little is known about the morbidity and outcome of such procedures in the elderly. This study compared the results of surgery for evaluating the effect of age on esophageal cancer patients. Methods: Patients who underwent surgery with curative intent for esophageal cancer from January 1999 to July 2009 were included in this retrospective study. Data were compared between patients ≥70 years (elderly group) and patients <70 years old (younger group). Patient characteristics, hospital course, surgical mortality, morbidity, and survival were compared between patients in these two age groups. Results: Of the 166 patients included, 35 (21.1%) were at least 70 years old (mean age, 75.2 years) and 131 (78.9%) were younger than 70 years old (mean age, 51.8 years). All 29 eligible elderly and 29 randomly selected, age-adjusted younger patients were included for a balanced comparison. The elderly group had significantly longer hospital stays (46 vs. 22 days) and a significantly higher incidence of surgical morbidity (51.7% vs. 20.7%). Cardiopulmonary-related complications were the main causes of operative morbidity in the elderly group. The elderly group also had higher performance state scores. On the basis of less adjuvant anticancer treatment received, the overall survival of elderly patients was comparable to their younger counterparts (12.1 vs. 12.7 months; p = 0.77). Conclusion: The results of this study suggest that curative surgery for esophageal cancer in elderly patients may result in comparable overall survival and greater, but acceptable, morbidity in comparison with younger patients. Our data suggest that age ≥70 years old should not be considered a counterindicator for curative surgery in esophageal cancer patients.http://www.sciencedirect.com/science/article/pii/S1873959810000086elderlyesophageal canceresophagectomy |
| spellingShingle | Hung-Chang Liu Yi-Ching Chen Chih-Hao Chen Yu-Jen Chen Esophagectomy in Elderly Patients With Esophageal Cancer International Journal of Gerontology elderly esophageal cancer esophagectomy |
| title | Esophagectomy in Elderly Patients With Esophageal Cancer |
| title_full | Esophagectomy in Elderly Patients With Esophageal Cancer |
| title_fullStr | Esophagectomy in Elderly Patients With Esophageal Cancer |
| title_full_unstemmed | Esophagectomy in Elderly Patients With Esophageal Cancer |
| title_short | Esophagectomy in Elderly Patients With Esophageal Cancer |
| title_sort | esophagectomy in elderly patients with esophageal cancer |
| topic | elderly esophageal cancer esophagectomy |
| url | http://www.sciencedirect.com/science/article/pii/S1873959810000086 |
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