A computational platform for high-throughput analysis of RNA sequences and modifications by mass spectrometry
Mass spectrometry (MS) enables identification of modified RNA residues, but high-throughput processing is currently a bottleneck. Here, the authors present a free and open-source database search engine for RNA MS data to facilitate reliable identification of modified RNA sequences.
Main Authors: | Samuel Wein, Byron Andrews, Timo Sachsenberg, Helena Santos-Rosa, Oliver Kohlbacher, Tony Kouzarides, Benjamin A. Garcia, Hendrik Weisser |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2020-02-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-020-14665-7 |
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