Modulating the Crosstalk between the Tumor and Its Microenvironment Using RNA Interference: A Treatment Strategy for Hepatocellular Carcinoma

Modulating the Crosstalk between the Tumor and Its Microenvironment Using RNA Interference: A Treatment Strategy for Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC) is the most common primary liver malignancy with one of the highest mortality rates among solid cancers. It develops almost exclusively in the background of chronic liver inflammation, which can be caused by viral hepatitis, chronic alcohol consumption or an unhealthy...

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Bibliographic Details
Main Authors: Mariam Mroweh, Thomas Decaens, Patrice N Marche, Zuzana Macek Jilkova, Flora Clément
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:International Journal of Molecular Sciences
Subjects:
HCC
tumor microenvironment
RNAi
miRNA
shRNA
siRNA
Online Access:https://www.mdpi.com/1422-0067/21/15/5250

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