Oxidized dietary lipids induce vascular inflammation and atherogenesis in post-menopausal rats: estradiol and selected antihyperlipidemic drugs restore vascular health in vivo

Oxidized dietary lipids induce vascular inflammation and atherogenesis in post-menopausal rats: estradiol and selected antihyperlipidemic drugs restore vascular health in vivo

Abstract Background Thermoxidation of edible oil through deep fat frying results in the generation of several oxidized products that promote lipid peroxidation and ROS production when eaten. Consumption of thermoxidized oil in post-menopausal conditions where the estrogen level is low contributes to...

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Bibliographic Details
Main Authors: Joy Temiloluwa Folahan, Olufunke Esan Olorundare, Abayomi Mayowa Ajayi, Adeoye Oyetunji Oyewopo, Sunday Sokunle Soyemi, Adejuwon Adewale Adeneye, Ikechukwu Innocent Okoye, Saheed Olanrewaju Afolabi, Anoka Ayembe Njan
Format: Article
Language:English
Published: BMC 2023-07-01
Series:Lipids in Health and Disease
Subjects:
Oxidized lipids
Vascular inflammation
Atherogenesis
Estrogen
Menopause
Antihyperlipidemic drugs
Online Access:https://doi.org/10.1186/s12944-023-01818-y

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