Myoepithelioma of parotid: A case report and review of literature
Myoepithelioma (ME) is a rarely encountered tumor of salivary gland accounting for about 1% of all salivary gland tumors. Though they were first identified long back, still their histopathologic features and immunohistochemistry (IHC) profile are not well characterized and there is no definitive cri...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2014-01-01
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| Series: | Journal of Oral Research and Review |
| Subjects: | |
| Online Access: | http://www.jorr.org/article.asp?issn=2249-4987;year=2014;volume=6;issue=2;spage=53;epage=56;aulast=Kapoor |
| _version_ | 1811264135517700096 |
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| author | Akhil Kapoor Prakash Singh Rajput Puneet Kumar Bagri Surender Beniwal Vanita Kumar Harvindra Singh Kumar |
| author_facet | Akhil Kapoor Prakash Singh Rajput Puneet Kumar Bagri Surender Beniwal Vanita Kumar Harvindra Singh Kumar |
| author_sort | Akhil Kapoor |
| collection | DOAJ |
| description | Myoepithelioma (ME) is a rarely encountered tumor of salivary gland accounting for about 1% of all salivary gland tumors. Though they were first identified long back, still their histopathologic features and immunohistochemistry (IHC) profile are not well characterized and there is no definitive criterion for this tumor with complex and varied features remaining a major barrier. We present a case of parotid enlargement in an 18-year-old girl in whom the IHC studies of superficial parotidectomy specimen revealed positive staining for Cytokeratin 5/6, HMW CK, Smooth muscle actin (SMA), S100, calponin, vimentin, and p63. CD45, EMA, CK7, carcinoembryonic antigen (CEA), BerEP4, GCDFP-15, and Glial fibrillary acidic protein (GFAP)-stained negative. With these IHC findings, the diagnosis of ME of parotid was established. This report highlights the importance of IHC studies along with a brief review of the literature. |
| first_indexed | 2024-04-12T19:58:42Z |
| format | Article |
| id | doaj.art-3d1a3653fc8644e6aaa6797001b7174e |
| institution | Directory Open Access Journal |
| issn | 2249-4987 2394-2541 |
| language | English |
| last_indexed | 2024-04-12T19:58:42Z |
| publishDate | 2014-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Oral Research and Review |
| spelling | doaj.art-3d1a3653fc8644e6aaa6797001b7174e2022-12-22T03:18:36ZengWolters Kluwer Medknow PublicationsJournal of Oral Research and Review2249-49872394-25412014-01-0162535610.4103/2249-4987.152910Myoepithelioma of parotid: A case report and review of literatureAkhil KapoorPrakash Singh RajputPuneet Kumar BagriSurender BeniwalVanita KumarHarvindra Singh KumarMyoepithelioma (ME) is a rarely encountered tumor of salivary gland accounting for about 1% of all salivary gland tumors. Though they were first identified long back, still their histopathologic features and immunohistochemistry (IHC) profile are not well characterized and there is no definitive criterion for this tumor with complex and varied features remaining a major barrier. We present a case of parotid enlargement in an 18-year-old girl in whom the IHC studies of superficial parotidectomy specimen revealed positive staining for Cytokeratin 5/6, HMW CK, Smooth muscle actin (SMA), S100, calponin, vimentin, and p63. CD45, EMA, CK7, carcinoembryonic antigen (CEA), BerEP4, GCDFP-15, and Glial fibrillary acidic protein (GFAP)-stained negative. With these IHC findings, the diagnosis of ME of parotid was established. This report highlights the importance of IHC studies along with a brief review of the literature.http://www.jorr.org/article.asp?issn=2249-4987;year=2014;volume=6;issue=2;spage=53;epage=56;aulast=KapoorHistopathologyimmunohistochemistrymyoepitheliomaparotid |
| spellingShingle | Akhil Kapoor Prakash Singh Rajput Puneet Kumar Bagri Surender Beniwal Vanita Kumar Harvindra Singh Kumar Myoepithelioma of parotid: A case report and review of literature Journal of Oral Research and Review Histopathology immunohistochemistry myoepithelioma parotid |
| title | Myoepithelioma of parotid: A case report and review of literature |
| title_full | Myoepithelioma of parotid: A case report and review of literature |
| title_fullStr | Myoepithelioma of parotid: A case report and review of literature |
| title_full_unstemmed | Myoepithelioma of parotid: A case report and review of literature |
| title_short | Myoepithelioma of parotid: A case report and review of literature |
| title_sort | myoepithelioma of parotid a case report and review of literature |
| topic | Histopathology immunohistochemistry myoepithelioma parotid |
| url | http://www.jorr.org/article.asp?issn=2249-4987;year=2014;volume=6;issue=2;spage=53;epage=56;aulast=Kapoor |
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