Toll‐Like Receptor (TLR)4 and MyD88 are Essential for Atheroprotection by Peritoneal B1a B Cells

Toll‐Like Receptor (TLR)4 and MyD88 are Essential for Atheroprotection by Peritoneal B1a B Cells

BackgroundWe previously identified peritoneal B1a cells that secrete natural IgM as a key atheroprotective B cell subset. However, the molecules that activate atheroprotective B1a cells are unknown. Here, we investigated whether Toll‐like receptors (TLRs) TLR2, TLR4, and TLR9 expressed by B1a cells...

Full description

Bibliographic Details
Main Authors: Hamid Hosseini, Yi Li, Peter Kanellakis, Christopher Tay, Anh Cao, Edgar Liu, Karlheinz Peter, Peter Tipping, Ban‐Hock Toh, Alex Bobik, Tin Kyaw
Format: Article
Language:English
Published: Wiley 2016-10-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
atherosclerosis
B1a cells
cytokine
IgM
inflammation
Toll‐like receptor 4/MyD88
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.115.002947

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.115.002947

Similar Items