PROTACs targeting epigenetic proteins

PROTACs targeting epigenetic proteins

The field of epigenetics pertains to alterations in gene function that are inherited without changes in the DNA sequence, including histone modifications, post-translational modifications of amino acids, and covalent modifications of DNA bases. These alteration pathways modulate the transformation o...

Full description

Bibliographic Details
Main Authors:	Chao Zhang, Yuna He, Xiuyun Sun, Wenyi Wei, Yanlong Liu, Yu Rao
Format:	Article
Language:	English
Published:	Compuscript Ltd 2023-12-01
Series:	Acta Materia Medica
Subjects:	protacs epigenetic protein degraders
Online Access:	https://www.scienceopen.com/hosted-document?doi=10.15212/AMM-2023-0039

Similar Items

PROTACs in Epigenetic Cancer Therapy: Current Status and Future Opportunities
by: Xuelian Liu, et al.
Published: (2023-01-01)

Non-small molecule PROTACs (NSM-PROTACs): Protein degradation kaleidoscope
by: Sinan Ma, et al.
Published: (2022-07-01)

Targeting Protein Kinases Degradation by PROTACs
by: Fei Yu, et al.
Published: (2021-06-01)

Overview of epigenetic degraders based on PROTAC, molecular glue, and hydrophobic tagging technologies
by: Xiaopeng Peng, et al.
Published: (2024-02-01)

Selective Degradation of Target Proteins by Chimeric Small-Molecular Drugs, PROTACs and SNIPERs
by: Minoru Ishikawa, et al.
Published: (2020-04-01)

Photocontrollable PROTAC molecules: Structure and mechanism of action
by: Koravović Mladen, et al.
Published: (2021-01-01)

Proteolysis-Targeting Chimeras (PROTACs) in Cancer Therapy: Present and Future
by: Rui Li, et al.
Published: (2022-12-01)

Ubiquitin recruiting chimera: more than just a PROTAC
by: Tatyana A. Grigoreva, et al.
Published: (2024-07-01)

PROTACs for BRDs proteins in cancer therapy: a review
by: Chao Wang, et al.
Published: (2022-12-01)

Novel approaches for the rational design of PROTAC linkers
by: Almaz Zagidullin, et al.
Published: (2020-10-01)

Proteolysis-targeting chimera (PROTAC) for targeted protein degradation and cancer therapy
by: Xin Li, et al.
Published: (2020-05-01)

Proteolysis targeting chimeras (PROTACs) in cancer therapy
by: Alberto Ocaña, et al.
Published: (2020-09-01)

Current strategies for the design of PROTAC linkers: a critical review
by: Robert I. Troup, et al.
Published: (2020-10-01)

Proteolysis-targeting chimaeras (PROTACs) as pharmacological tools and therapeutic agents: advances and future challenges
by: Chao Wang, et al.
Published: (2022-12-01)

From PROTAC to TPD: Advances and Opportunities in Targeted Protein Degradation
by: Siqi Wang, et al.
Published: (2024-01-01)

Targeted Protein Degradation by Chimeric Small Molecules, PROTACs and SNIPERs
by: Mikihiko Naito, et al.
Published: (2019-12-01)

PROTAC technology for the treatment of Alzheimer’s disease: advances and perspectives
by: Hiroyuki Inuzuka, et al.
Published: (2022-01-01)

Estrogen Receptor-α Targeting: PROTACs, SNIPERs, Peptide-PROTACs, Antibody Conjugated PROTACs and SNIPERs
by: Arvind Negi, et al.
Published: (2022-11-01)

Proteolysis-targeting chimeras (PROTACs) in cancer therapy
by: Xinyi Li, et al.
Published: (2022-04-01)

Modeling PROTAC degradation activity with machine learning
by: Stefano Ribes, et al.
Published: (2024-12-01)

Recent Advances in PROTAC-Based Antiviral Strategies
by: Haleema Ahmad, et al.
Published: (2023-01-01)

Recent Advances in Optically Controlled PROTAC
by: Muzi Ouyang, et al.
Published: (2023-11-01)

PROTACs: Emerging Targeted Protein Degradation Approaches for Advanced Druggable Strategies
by: Nuwayo Ishimwe Sincere, et al.
Published: (2023-05-01)

PROTAC: An Effective Targeted Protein Degradation Strategy for Cancer Therapy
by: Si-Min Qi, et al.
Published: (2021-05-01)

An overview of PROTACs: a promising drug discovery paradigm
by: Zi Liu, et al.
Published: (2022-12-01)

Precision-engineered PROTACs minimize off-tissue effects in cancer therapy
by: Jianghua Shi, et al.
Published: (2024-11-01)

PROTAC vaccine: A new way to live attenuated vaccines
by: Zhen Li, et al.
Published: (2022-10-01)

PROTACs in gastrointestinal cancers
by: Yu Chen, et al.
Published: (2022-12-01)

Design, synthesis, and biological evaluation of potent FAK-degrading PROTACs
by: Qiaohua Qin, et al.
Published: (2022-12-01)

Mapping the energy landscape of PROTAC-mediated protein-protein interactions
by: José A. Villegas, et al.
Published: (2023-01-01)

Orthogonal validation of PROTAC mediated degradation of the integral membrane proteins EGFR and c-MET
by: Camilla Ruffilli, et al.
Published: (2025-01-01)

PROteolysis‐Targeting Chimeras (PROTACs) in leukemia: overview and future perspectives
by: André T. S. Vicente, et al.
Published: (2024-06-01)

Versatile Nano‐PROTAC‐Induced Epigenetic Reader Degradation for Efficient Lung Cancer Therapy
by: Huan‐Tian Zhang, et al.
Published: (2022-10-01)

Recent advances in IAP-based PROTACs (SNIPERs) as potential therapeutic agents
by: Chao Wang, et al.
Published: (2022-12-01)

Application of PROTACs in target identification and validation
by: Yang Liu, et al.
Published: (2024-03-01)

Corrigendum to “Modeling PROTAC degradation activity with machine learning” [Artif. Intell. Life Sci. 6 (2024) 100104]
by: Stefano Ribes, et al.
Published: (2024-12-01)

Recent advances of PROTACs technology in neurodegenerative diseases
by: Chao Wang, et al.
Published: (2023-09-01)

New-generation advanced PROTACs as potential therapeutic agents in cancer therapy
by: Chao Wang, et al.
Published: (2024-05-01)

Design, Synthesis, and Biological Evaluation of Proteolysis Targeting Chimeras (PROTACs) for the Dual Degradation of IGF-1R and Src
by: Sudhakar Manda, et al.
Published: (2020-04-01)

Central Nervous System Targeted Protein Degraders
by: Bedwyr ab Ion Thomas, et al.
Published: (2023-07-01)