Hemostasis and Post-operative Care of Oral Surgical Wounds by Hemcon Dental Dressing in Patients on Oral Anticoagulant Therapy: A Split Mouth Randomized Controlled Clinical Trial
Introduction: Hemostasis is a fundamental management issue post-operatively in minor oral surgical procedures. To ensure safety and therapeutic efficacy in patients, under oral anti coagulant therapy, is complicated by necessity for frequent determination of prothrombin time or international nor...
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| Format: | Article |
| Language: | English |
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JCDR Research and Publications Private Limited
2016-09-01
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| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://jcdr.net/articles/PDF/8462/17275_CE(EK)_F(AK)_PF1(NEAK)_PFA(AK)_PF2(PAG).pdf |
| _version_ | 1818041771403247616 |
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| author | K.R. Ashok Kumar Jambukeshwar Kumar Jagadesh Sarvagna Praveen Gadde Shwetha Chikkaboriah |
| author_facet | K.R. Ashok Kumar Jambukeshwar Kumar Jagadesh Sarvagna Praveen Gadde Shwetha Chikkaboriah |
| author_sort | K.R. Ashok Kumar |
| collection | DOAJ |
| description | Introduction: Hemostasis is a fundamental management issue
post-operatively in minor oral surgical procedures. To ensure
safety and therapeutic efficacy in patients, under oral anti
coagulant therapy, is complicated by necessity for frequent
determination of prothrombin time or international normalised
ratio.
Aim: The aim of the study was to determine whether early
hemostasis achieved by using Hemcon Dental Dressing (HDD)
will affect post-operative care and surgical healing outcome in
minor oral surgical procedures.
Materials and Methods: A total of 30 patients, aged 18 years
to 90 years, except those allergic to seafood, who consented to
participate, were enrolled into this study. Patients were required
to have two or more surgical sites so that they would have both
surgical and control sites. All patients taking Oral Anticoagulation
Therapy (OAT) were included for treatment in the study without
altering the anticoagulant regimens. Institutional Review Board
approval was obtained for the same. The collected data was
subjected to statistical analysis using unpaired t-test.
Results: All HDD surgically treated sites achieved hemostasis
in 1.49 minutes and control wounds in 4.06 minutes (p < 0.001).
Post-operative pain at HDD treated sites (1.87,1.27 on 1st and
3rd day respectively) was significantly lower than the control
sites (4.0,1.87 on 1st and 3rd day respectively) p-value (0.001,
0.001 respectively). HDD treated oral surgery wounds achieved
statistically significant improved healing both at 1st and 3rd postoperative days (p <0.0001).
Conclusion: The HDD has been proven to be a clinically
effective hemostatic dressing material that significantly shortens
bleeding time following minor oral surgical procedures under
local anaesthesia, including those patients taking OAT. Patients
receiving the HDD had improved surgical wound healing as
compared to controls. |
| first_indexed | 2024-12-10T08:35:43Z |
| format | Article |
| id | doaj.art-3d2130c3d46946569cab97d99fa29165 |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-12-10T08:35:43Z |
| publishDate | 2016-09-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-3d2130c3d46946569cab97d99fa291652022-12-22T01:55:59ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2016-09-01109ZC37ZC4010.7860/JCDR/2016/17275.8462Hemostasis and Post-operative Care of Oral Surgical Wounds by Hemcon Dental Dressing in Patients on Oral Anticoagulant Therapy: A Split Mouth Randomized Controlled Clinical TrialK.R. Ashok Kumar0Jambukeshwar Kumar1Jagadesh Sarvagna2Praveen Gadde3Shwetha Chikkaboriah4Head of the Department, Department of Oral and Maxillofacial Surgery, Sri Siddhartha Dental College, Tumkur, Karnataka, India.Senior Lecturer, Department of Oral and Maxillofacial Surgery, Vishnu Dental Collage, Bhimavaram, Andhra Pradesh, India.Consultant Oral Oncologist, Siddhagiri Hospital, Kolhapur, Maharashtra, India.Senior Lecturer, Department of Public Health Dentistry, Vishnu Dental College, Bhimavaram, Andhrapradesh, India.Postgraduate, Department of Periodontics, Vakkaligara Sanga Dental College, Bangalore, Karnataka, India.Introduction: Hemostasis is a fundamental management issue post-operatively in minor oral surgical procedures. To ensure safety and therapeutic efficacy in patients, under oral anti coagulant therapy, is complicated by necessity for frequent determination of prothrombin time or international normalised ratio. Aim: The aim of the study was to determine whether early hemostasis achieved by using Hemcon Dental Dressing (HDD) will affect post-operative care and surgical healing outcome in minor oral surgical procedures. Materials and Methods: A total of 30 patients, aged 18 years to 90 years, except those allergic to seafood, who consented to participate, were enrolled into this study. Patients were required to have two or more surgical sites so that they would have both surgical and control sites. All patients taking Oral Anticoagulation Therapy (OAT) were included for treatment in the study without altering the anticoagulant regimens. Institutional Review Board approval was obtained for the same. The collected data was subjected to statistical analysis using unpaired t-test. Results: All HDD surgically treated sites achieved hemostasis in 1.49 minutes and control wounds in 4.06 minutes (p < 0.001). Post-operative pain at HDD treated sites (1.87,1.27 on 1st and 3rd day respectively) was significantly lower than the control sites (4.0,1.87 on 1st and 3rd day respectively) p-value (0.001, 0.001 respectively). HDD treated oral surgery wounds achieved statistically significant improved healing both at 1st and 3rd postoperative days (p <0.0001). Conclusion: The HDD has been proven to be a clinically effective hemostatic dressing material that significantly shortens bleeding time following minor oral surgical procedures under local anaesthesia, including those patients taking OAT. Patients receiving the HDD had improved surgical wound healing as compared to controls.https://jcdr.net/articles/PDF/8462/17275_CE(EK)_F(AK)_PF1(NEAK)_PFA(AK)_PF2(PAG).pdfbleedingchitosan dressingextraction wound healinginternational normalised ratiominor oral surgery |
| spellingShingle | K.R. Ashok Kumar Jambukeshwar Kumar Jagadesh Sarvagna Praveen Gadde Shwetha Chikkaboriah Hemostasis and Post-operative Care of Oral Surgical Wounds by Hemcon Dental Dressing in Patients on Oral Anticoagulant Therapy: A Split Mouth Randomized Controlled Clinical Trial Journal of Clinical and Diagnostic Research bleeding chitosan dressing extraction wound healing international normalised ratio minor oral surgery |
| title | Hemostasis and Post-operative Care of Oral Surgical Wounds by Hemcon Dental Dressing in Patients on Oral Anticoagulant Therapy: A Split Mouth Randomized Controlled Clinical Trial |
| title_full | Hemostasis and Post-operative Care of Oral Surgical Wounds by Hemcon Dental Dressing in Patients on Oral Anticoagulant Therapy: A Split Mouth Randomized Controlled Clinical Trial |
| title_fullStr | Hemostasis and Post-operative Care of Oral Surgical Wounds by Hemcon Dental Dressing in Patients on Oral Anticoagulant Therapy: A Split Mouth Randomized Controlled Clinical Trial |
| title_full_unstemmed | Hemostasis and Post-operative Care of Oral Surgical Wounds by Hemcon Dental Dressing in Patients on Oral Anticoagulant Therapy: A Split Mouth Randomized Controlled Clinical Trial |
| title_short | Hemostasis and Post-operative Care of Oral Surgical Wounds by Hemcon Dental Dressing in Patients on Oral Anticoagulant Therapy: A Split Mouth Randomized Controlled Clinical Trial |
| title_sort | hemostasis and post operative care of oral surgical wounds by hemcon dental dressing in patients on oral anticoagulant therapy a split mouth randomized controlled clinical trial |
| topic | bleeding chitosan dressing extraction wound healing international normalised ratio minor oral surgery |
| url | https://jcdr.net/articles/PDF/8462/17275_CE(EK)_F(AK)_PF1(NEAK)_PFA(AK)_PF2(PAG).pdf |
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