A comparative study of wave 1 and 2 mortality factors among COVID-19 patients in a level 3 medical college hospital in Saharanpur India

Background: In COVID-19, second wave death rate climbed in several states of India including Uttar Pradesh with relatively high number of casualties as compared to first wave. The literature lacks scientific reason behind this. Aims and Objectives: The present study aimed toward detection of mort...

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Main Authors: Devinder Kumar Vohra, Nawab Singh, Manchanda JK, Sanjeev Davey, Arvind Trivedi, Anuradha Dave, Kayanat Nasser
Format: Article
Language:English
Published: Manipal College of Medical Sciences, Pokhara 2022-05-01
Series:Asian Journal of Medical Sciences
Subjects:
Online Access:https://www.nepjol.info/index.php/AJMS/article/view/41558
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author Devinder Kumar Vohra
Nawab Singh
Manchanda JK
Sanjeev Davey
Arvind Trivedi
Anuradha Dave
Kayanat Nasser
author_facet Devinder Kumar Vohra
Nawab Singh
Manchanda JK
Sanjeev Davey
Arvind Trivedi
Anuradha Dave
Kayanat Nasser
author_sort Devinder Kumar Vohra
collection DOAJ
description Background: In COVID-19, second wave death rate climbed in several states of India including Uttar Pradesh with relatively high number of casualties as compared to first wave. The literature lacks scientific reason behind this. Aims and Objectives: The present study aimed toward detection of mortality factors for COVID-19 patients from a Level 3 Medical College Hospital in both waves in Western UP District in India so as to find a better treatment strategies for COVID-19 patients for possible next 3rd COVID-19 wave. Materials and Methods: This study is aimed to find any difference in Wave 1 and 2 mortality factors among COVID-19 patients in a Level 3 Medical College Hospital in western up district Saharanpur in India from April 1, 2020 to Sep 30, 2021. Results: Although there were more number of deaths in Wave 2 (n=537) as compared to Wave 1 (n=172), deaths even after treatment of COVID-19 were more in wave 1 (72%) as compared to wave 2 (67.9%), but it was not statistically significant (P>0.05). In COVID -19, Wave 1 most of the patients were elderly (aged >60 years) (40.3%) whereas in Wave 2 45–60 years age group were more affected (40.5%). Presence of more than 2 comorbidities was also seen more in wave 1 (37.1%) as compared to Wave 2 (23.8%). In COVID-19, both Waves (1 and 2) the most common co-morbidity was Type2DM (52% and 36.4%, respectively), but DM was found to be more in COVID+ve patients of Wave 1 as compared to wave 2 COVID+ve patients whereas any CARDIAC abnormality co-morbidity was found more in Wave 2 patients as compared to Wave 1 (14.2% vs. 12.1%). Conclusion: Possibly COVID-19 virus operated differently at Cardio-respiratory system leading to increased mortality in COVID-19 patients in Wave 2.
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spelling doaj.art-3d22c8dbe5314d418deacf9fc5a585a52022-12-22T03:03:58ZengManipal College of Medical Sciences, PokharaAsian Journal of Medical Sciences2467-91002091-05762022-05-0113516https://doi.org/10.3126/ajms.v13i5.41558A comparative study of wave 1 and 2 mortality factors among COVID-19 patients in a level 3 medical college hospital in Saharanpur IndiaDevinder Kumar Vohra 0Nawab Singh 1Manchanda JK 2Sanjeev Davey 3https://orcid.org/0000-0002-1062-4322Arvind Trivedi 4Anuradha Dave 5Kayanat Nasser 6Associate Professor and Head, Department of Medicine, SMMH, Government Medical College, SaharanpurAssociate Professor and Head, Department of Anesthesia, SMMH, Government Medical College, SaharanpurAssisstant Professor and Head, Department of Ophthalmology, SMMH, Government Medical College, SaharanpurProfessor and Head, Department of Community Medicine, SMMH, Government Medical College, Saharanpur Principal, Department of Nephrology, SMMH, Government Medical College, SaharanpurProfessor, Department of Community Medicine, Subharti Medical College, Meerut, Uttar Pradesh, IndiaStatistician, Department of Community Medicine, Subharti Medical College, Meerut, Uttar Pradesh, IndiaBackground: In COVID-19, second wave death rate climbed in several states of India including Uttar Pradesh with relatively high number of casualties as compared to first wave. The literature lacks scientific reason behind this. Aims and Objectives: The present study aimed toward detection of mortality factors for COVID-19 patients from a Level 3 Medical College Hospital in both waves in Western UP District in India so as to find a better treatment strategies for COVID-19 patients for possible next 3rd COVID-19 wave. Materials and Methods: This study is aimed to find any difference in Wave 1 and 2 mortality factors among COVID-19 patients in a Level 3 Medical College Hospital in western up district Saharanpur in India from April 1, 2020 to Sep 30, 2021. Results: Although there were more number of deaths in Wave 2 (n=537) as compared to Wave 1 (n=172), deaths even after treatment of COVID-19 were more in wave 1 (72%) as compared to wave 2 (67.9%), but it was not statistically significant (P>0.05). In COVID -19, Wave 1 most of the patients were elderly (aged >60 years) (40.3%) whereas in Wave 2 45–60 years age group were more affected (40.5%). Presence of more than 2 comorbidities was also seen more in wave 1 (37.1%) as compared to Wave 2 (23.8%). In COVID-19, both Waves (1 and 2) the most common co-morbidity was Type2DM (52% and 36.4%, respectively), but DM was found to be more in COVID+ve patients of Wave 1 as compared to wave 2 COVID+ve patients whereas any CARDIAC abnormality co-morbidity was found more in Wave 2 patients as compared to Wave 1 (14.2% vs. 12.1%). Conclusion: Possibly COVID-19 virus operated differently at Cardio-respiratory system leading to increased mortality in COVID-19 patients in Wave 2.https://www.nepjol.info/index.php/AJMS/article/view/41558covid-19hypertensionlevel 3 hospitalmortalityt2dmwave 1wave 2
spellingShingle Devinder Kumar Vohra
Nawab Singh
Manchanda JK
Sanjeev Davey
Arvind Trivedi
Anuradha Dave
Kayanat Nasser
A comparative study of wave 1 and 2 mortality factors among COVID-19 patients in a level 3 medical college hospital in Saharanpur India
Asian Journal of Medical Sciences
covid-19
hypertension
level 3 hospital
mortality
t2dm
wave 1
wave 2
title A comparative study of wave 1 and 2 mortality factors among COVID-19 patients in a level 3 medical college hospital in Saharanpur India
title_full A comparative study of wave 1 and 2 mortality factors among COVID-19 patients in a level 3 medical college hospital in Saharanpur India
title_fullStr A comparative study of wave 1 and 2 mortality factors among COVID-19 patients in a level 3 medical college hospital in Saharanpur India
title_full_unstemmed A comparative study of wave 1 and 2 mortality factors among COVID-19 patients in a level 3 medical college hospital in Saharanpur India
title_short A comparative study of wave 1 and 2 mortality factors among COVID-19 patients in a level 3 medical college hospital in Saharanpur India
title_sort comparative study of wave 1 and 2 mortality factors among covid 19 patients in a level 3 medical college hospital in saharanpur india
topic covid-19
hypertension
level 3 hospital
mortality
t2dm
wave 1
wave 2
url https://www.nepjol.info/index.php/AJMS/article/view/41558
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