Synthesis of 3,4-Dibenzyltetrahydrofuran Lignans (9,9′-Epoxylignanes)
Different strategies for the racemic or enantiospecific total syntheses of plant and mammalian 3,4-dibenzyltetrahydrofuran lignans are reviewed and compared. The multi-step approaches have various key step strategies: Diels–Alder reactions, Stobbe condensations, Michael additions, alkylations, nitri...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2013-10-01
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| Series: | Molecules |
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| Online Access: | http://www.mdpi.com/1420-3049/18/11/13124 |
| _version_ | 1818257907095961600 |
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| author | Kristiina Wähälä Monika Pohjoispää |
| author_facet | Kristiina Wähälä Monika Pohjoispää |
| author_sort | Kristiina Wähälä |
| collection | DOAJ |
| description | Different strategies for the racemic or enantiospecific total syntheses of plant and mammalian 3,4-dibenzyltetrahydrofuran lignans are reviewed and compared. The multi-step approaches have various key step strategies: Diels–Alder reactions, Stobbe condensations, Michael additions, alkylations, nitrile oxide cycloadditions, radical cyclisations, dianion and oxidative couplings. |
| first_indexed | 2024-12-12T17:51:06Z |
| format | Article |
| id | doaj.art-3d25287c9578412b94d5e19c4db2b48b |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-12-12T17:51:06Z |
| publishDate | 2013-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-3d25287c9578412b94d5e19c4db2b48b2022-12-22T00:16:49ZengMDPI AGMolecules1420-30492013-10-011811131241313810.3390/molecules181113124Synthesis of 3,4-Dibenzyltetrahydrofuran Lignans (9,9′-Epoxylignanes)Kristiina WähäläMonika PohjoispääDifferent strategies for the racemic or enantiospecific total syntheses of plant and mammalian 3,4-dibenzyltetrahydrofuran lignans are reviewed and compared. The multi-step approaches have various key step strategies: Diels–Alder reactions, Stobbe condensations, Michael additions, alkylations, nitrile oxide cycloadditions, radical cyclisations, dianion and oxidative couplings.http://www.mdpi.com/1420-3049/18/11/13124lignantrans-3,4-dibenzyltetrahydrofurantetrahydrofuran9,9'-epoxylignanesynthesis |
| spellingShingle | Kristiina Wähälä Monika Pohjoispää Synthesis of 3,4-Dibenzyltetrahydrofuran Lignans (9,9′-Epoxylignanes) Molecules lignan trans-3,4-dibenzyltetrahydrofuran tetrahydrofuran 9,9'-epoxylignane synthesis |
| title | Synthesis of 3,4-Dibenzyltetrahydrofuran Lignans (9,9′-Epoxylignanes) |
| title_full | Synthesis of 3,4-Dibenzyltetrahydrofuran Lignans (9,9′-Epoxylignanes) |
| title_fullStr | Synthesis of 3,4-Dibenzyltetrahydrofuran Lignans (9,9′-Epoxylignanes) |
| title_full_unstemmed | Synthesis of 3,4-Dibenzyltetrahydrofuran Lignans (9,9′-Epoxylignanes) |
| title_short | Synthesis of 3,4-Dibenzyltetrahydrofuran Lignans (9,9′-Epoxylignanes) |
| title_sort | synthesis of 3 4 dibenzyltetrahydrofuran lignans 9 9 epoxylignanes |
| topic | lignan trans-3,4-dibenzyltetrahydrofuran tetrahydrofuran 9,9'-epoxylignane synthesis |
| url | http://www.mdpi.com/1420-3049/18/11/13124 |
| work_keys_str_mv | AT kristiinawahala synthesisof34dibenzyltetrahydrofuranlignans99epoxylignanes AT monikapohjoispaa synthesisof34dibenzyltetrahydrofuranlignans99epoxylignanes |