Para-Bombay phenotype: A case report from a tertiary care hospital from South Gujarat

The blood specimen of a 30-year-old male donor showing a discrepancy in cell and serum grouping was targeted for detailed study at the blood bank at tertiary care hospital in South Gujarat. Forward grouping showed group as “O” RhD positive and reverse grouping as group “A.” Further testing confirmed...

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Main Authors: Jitendra N Patel, Ajaykumar B Donta, Arpit C Patel, Amrish N Pandya, Swati S Kulkarni
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2018-01-01
Series:Asian Journal of Transfusion Science
Subjects:
Online Access:http://www.ajts.org/article.asp?issn=0973-6247;year=2018;volume=12;issue=2;spage=180;epage=182;aulast=Patel
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author Jitendra N Patel
Ajaykumar B Donta
Arpit C Patel
Amrish N Pandya
Swati S Kulkarni
author_facet Jitendra N Patel
Ajaykumar B Donta
Arpit C Patel
Amrish N Pandya
Swati S Kulkarni
author_sort Jitendra N Patel
collection DOAJ
description The blood specimen of a 30-year-old male donor showing a discrepancy in cell and serum grouping was targeted for detailed study at the blood bank at tertiary care hospital in South Gujarat. Forward grouping showed group as “O” RhD positive and reverse grouping as group “A.” Further testing confirmed that the individual's blood group was para-Bombay A (para-AH). Family members were screened, and younger brother was also identified as para-Bombay phenotype. The para-Bombay phenotype is very rare, and only a few cases have been reported from India. This blood group is characterized by the absence of ABH antigens on red blood cells (RBC's) with the presence of ABH substances in body secretions or by the weak expression of ABH antigens on RBC's with the absence or presence of substances in body secretions. This rare phenotype can be mislabeled as “O” if all detailed investigations are not performed.
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spelling doaj.art-3d2a132703594cbbba55602f3dd29fea2022-12-21T18:29:42ZengWolters Kluwer Medknow PublicationsAsian Journal of Transfusion Science0973-62471998-35652018-01-0112218018210.4103/ajts.AJTS_151_17Para-Bombay phenotype: A case report from a tertiary care hospital from South GujaratJitendra N PatelAjaykumar B DontaArpit C PatelAmrish N PandyaSwati S KulkarniThe blood specimen of a 30-year-old male donor showing a discrepancy in cell and serum grouping was targeted for detailed study at the blood bank at tertiary care hospital in South Gujarat. Forward grouping showed group as “O” RhD positive and reverse grouping as group “A.” Further testing confirmed that the individual's blood group was para-Bombay A (para-AH). Family members were screened, and younger brother was also identified as para-Bombay phenotype. The para-Bombay phenotype is very rare, and only a few cases have been reported from India. This blood group is characterized by the absence of ABH antigens on red blood cells (RBC's) with the presence of ABH substances in body secretions or by the weak expression of ABH antigens on RBC's with the absence or presence of substances in body secretions. This rare phenotype can be mislabeled as “O” if all detailed investigations are not performed.http://www.ajts.org/article.asp?issn=0973-6247;year=2018;volume=12;issue=2;spage=180;epage=182;aulast=PatelH-antigenpara-Bombaysecretor status
spellingShingle Jitendra N Patel
Ajaykumar B Donta
Arpit C Patel
Amrish N Pandya
Swati S Kulkarni
Para-Bombay phenotype: A case report from a tertiary care hospital from South Gujarat
Asian Journal of Transfusion Science
H-antigen
para-Bombay
secretor status
title Para-Bombay phenotype: A case report from a tertiary care hospital from South Gujarat
title_full Para-Bombay phenotype: A case report from a tertiary care hospital from South Gujarat
title_fullStr Para-Bombay phenotype: A case report from a tertiary care hospital from South Gujarat
title_full_unstemmed Para-Bombay phenotype: A case report from a tertiary care hospital from South Gujarat
title_short Para-Bombay phenotype: A case report from a tertiary care hospital from South Gujarat
title_sort para bombay phenotype a case report from a tertiary care hospital from south gujarat
topic H-antigen
para-Bombay
secretor status
url http://www.ajts.org/article.asp?issn=0973-6247;year=2018;volume=12;issue=2;spage=180;epage=182;aulast=Patel
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AT arpitcpatel parabombayphenotypeacasereportfromatertiarycarehospitalfromsouthgujarat
AT amrishnpandya parabombayphenotypeacasereportfromatertiarycarehospitalfromsouthgujarat
AT swatiskulkarni parabombayphenotypeacasereportfromatertiarycarehospitalfromsouthgujarat