A review of calcium phosphate cements and acrylic bone cements as injectable materials for bone repair and implant fixation
Treatment of bone defects caused by trauma or disease is a major burden on human healthcare systems. Although autologous bone grafts are considered as the gold standard, they are limited in availability and are associated with post-operative complications. Minimally invasive alternatives using injec...
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2019-11-01
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| Series: | Journal of Applied Biomaterials & Functional Materials |
| Online Access: | https://doi.org/10.1177/2280800019872594 |
| _version_ | 1819045900759072768 |
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| author | Azizeh-Mitra Yousefi |
| author_facet | Azizeh-Mitra Yousefi |
| author_sort | Azizeh-Mitra Yousefi |
| collection | DOAJ |
| description | Treatment of bone defects caused by trauma or disease is a major burden on human healthcare systems. Although autologous bone grafts are considered as the gold standard, they are limited in availability and are associated with post-operative complications. Minimally invasive alternatives using injectable bone cements are currently used in certain clinical procedures, such as vertebroplasty and balloon kyphoplasty. Nevertheless, given the high incidence of fractures and pathologies that result in bone voids, there is an unmet need for injectable materials with desired properties for minimally invasive procedures. This paper provides an overview of the most common injectable bone cement materials for clinical use. The emphasis has been placed on calcium phosphate cements and acrylic bone cements, while enabling the readers to compare the opportunities and challenges for these two classes of bone cements. This paper also briefly reviews antibiotic-loaded bone cements used in bone repair and implant fixation, including their efficacy and cost for healthcare systems. A summary of the current challenges and recommendations for future directions has been brought in the concluding section of this paper. |
| first_indexed | 2024-12-21T10:35:55Z |
| format | Article |
| id | doaj.art-3d2a3f23f404403d8b5de4d7645fd4d7 |
| institution | Directory Open Access Journal |
| issn | 2280-8000 |
| language | English |
| last_indexed | 2024-12-21T10:35:55Z |
| publishDate | 2019-11-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Journal of Applied Biomaterials & Functional Materials |
| spelling | doaj.art-3d2a3f23f404403d8b5de4d7645fd4d72022-12-21T19:07:04ZengSAGE PublishingJournal of Applied Biomaterials & Functional Materials2280-80002019-11-011710.1177/2280800019872594A review of calcium phosphate cements and acrylic bone cements as injectable materials for bone repair and implant fixationAzizeh-Mitra YousefiTreatment of bone defects caused by trauma or disease is a major burden on human healthcare systems. Although autologous bone grafts are considered as the gold standard, they are limited in availability and are associated with post-operative complications. Minimally invasive alternatives using injectable bone cements are currently used in certain clinical procedures, such as vertebroplasty and balloon kyphoplasty. Nevertheless, given the high incidence of fractures and pathologies that result in bone voids, there is an unmet need for injectable materials with desired properties for minimally invasive procedures. This paper provides an overview of the most common injectable bone cement materials for clinical use. The emphasis has been placed on calcium phosphate cements and acrylic bone cements, while enabling the readers to compare the opportunities and challenges for these two classes of bone cements. This paper also briefly reviews antibiotic-loaded bone cements used in bone repair and implant fixation, including their efficacy and cost for healthcare systems. A summary of the current challenges and recommendations for future directions has been brought in the concluding section of this paper.https://doi.org/10.1177/2280800019872594 |
| spellingShingle | Azizeh-Mitra Yousefi A review of calcium phosphate cements and acrylic bone cements as injectable materials for bone repair and implant fixation Journal of Applied Biomaterials & Functional Materials |
| title | A review of calcium phosphate cements and acrylic bone cements as injectable materials for bone repair and implant fixation |
| title_full | A review of calcium phosphate cements and acrylic bone cements as injectable materials for bone repair and implant fixation |
| title_fullStr | A review of calcium phosphate cements and acrylic bone cements as injectable materials for bone repair and implant fixation |
| title_full_unstemmed | A review of calcium phosphate cements and acrylic bone cements as injectable materials for bone repair and implant fixation |
| title_short | A review of calcium phosphate cements and acrylic bone cements as injectable materials for bone repair and implant fixation |
| title_sort | review of calcium phosphate cements and acrylic bone cements as injectable materials for bone repair and implant fixation |
| url | https://doi.org/10.1177/2280800019872594 |
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