The role of interleukin genes in the course of depression
Research studies conducted in recent years have confirmed that in the absence of medical illnesses, depressive disorders are associated with upregulation of many inflammatory cytokines such as tumor necrosis factor-aplha (TNF-α), interleukin-1 and 6 (IL-1,IL-6). The main objective of the study was t...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
De Gruyter
2016-01-01
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| Series: | Open Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1515/med-2016-0009 |
| _version_ | 1818731332066344960 |
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| author | Talarowska Monika Szemraj Janusz Gałecki Piotr |
| author_facet | Talarowska Monika Szemraj Janusz Gałecki Piotr |
| author_sort | Talarowska Monika |
| collection | DOAJ |
| description | Research studies conducted in recent years have confirmed that in the absence of medical illnesses, depressive disorders are associated with upregulation of many inflammatory cytokines such as tumor necrosis factor-aplha (TNF-α), interleukin-1 and 6 (IL-1,IL-6). The main objective of the study was to examine whether recurrent depressive disorders (rDD) are accompanied by more profound inflammatory disturbances than the first episode of depression (ED-I). The analysis included the expression of mRNA and protein levels of three interleukins namely. IL-1, IL-6 and IL-10. |
| first_indexed | 2024-12-17T23:15:59Z |
| format | Article |
| id | doaj.art-3d2e7bddddaa45c99269390d792a12d6 |
| institution | Directory Open Access Journal |
| issn | 2391-5463 |
| language | English |
| last_indexed | 2024-12-17T23:15:59Z |
| publishDate | 2016-01-01 |
| publisher | De Gruyter |
| record_format | Article |
| series | Open Medicine |
| spelling | doaj.art-3d2e7bddddaa45c99269390d792a12d62022-12-21T21:29:01ZengDe GruyterOpen Medicine2391-54632016-01-01111414810.1515/med-2016-0009med-2016-0009The role of interleukin genes in the course of depressionTalarowska Monika0Szemraj Janusz1Gałecki Piotr2Department of Adult Psychiatry, Medical University of Lodz, Lodz, PolandDepartment of Medical Biochemistry, Medical University of Lodz, Lodz, PolandDepartment of Adult Psychiatry, Medical University of Lodz, Lodz, PolandResearch studies conducted in recent years have confirmed that in the absence of medical illnesses, depressive disorders are associated with upregulation of many inflammatory cytokines such as tumor necrosis factor-aplha (TNF-α), interleukin-1 and 6 (IL-1,IL-6). The main objective of the study was to examine whether recurrent depressive disorders (rDD) are accompanied by more profound inflammatory disturbances than the first episode of depression (ED-I). The analysis included the expression of mRNA and protein levels of three interleukins namely. IL-1, IL-6 and IL-10.https://doi.org/10.1515/med-2016-0009first episoderecurrent depressive disorderil-1il-6il-10 |
| spellingShingle | Talarowska Monika Szemraj Janusz Gałecki Piotr The role of interleukin genes in the course of depression Open Medicine first episode recurrent depressive disorder il-1 il-6 il-10 |
| title | The role of interleukin genes in the course of depression |
| title_full | The role of interleukin genes in the course of depression |
| title_fullStr | The role of interleukin genes in the course of depression |
| title_full_unstemmed | The role of interleukin genes in the course of depression |
| title_short | The role of interleukin genes in the course of depression |
| title_sort | role of interleukin genes in the course of depression |
| topic | first episode recurrent depressive disorder il-1 il-6 il-10 |
| url | https://doi.org/10.1515/med-2016-0009 |
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