SLAMF7/STAT6 Pathway Inhibits Innate Immune Response in Late-Stage Human <i>Acanthamoeba</i> Keratitis: A Comparative Transcriptome Analysis

SLAMF7/STAT6 Pathway Inhibits Innate Immune Response in Late-Stage Human <i>Acanthamoeba</i> Keratitis: A Comparative Transcriptome Analysis

<i>Acanthamoeba</i> keratitis (AK) is a blinding corneal infection caused by the protozoan <i>Acanthamoeba</i>. The long-term course of AK suggests the host immunity could not kill <i>Acanthamoeba</i> rapidly. The immune status is still unclear in the late stage o...

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Bibliographic Details
Main Authors: Zhenyu Wei, Yuheng Zhang, Qiankun Chen, Xizhan Xu, Zhiqiang Pan, Zi-Bing Jin, Qingfeng Liang
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Microorganisms
Subjects:
<i>Acanthamoeba</i> keratitis
transcriptome analysis
immune status
differentially expressed genes
pathway enrichment
Online Access:https://www.mdpi.com/2076-2607/11/2/365

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