Pheochromocytoma in pregnancy – a rare but dangerous diagnosis
Pheochromocytoma is a rare cause of hypertension in pregnancy. Unrecognized, it carries a great risk for both mother and the foetus. The main reason for missing the diagnosis is the misconception that any hypertension occurring in pregnancy is gestational hypertension or pre (eclampsia). As many as...
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| Format: | Article |
| Language: | English |
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Medical Association of Zenica-Doboj Canton
2022-08-01
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| Series: | Medicinski Glasnik |
| Subjects: | |
| Online Access: | https://ljkzedo.ba/mgpdf/mg37/07_Marusic_1474_A.pdf |
| _version_ | 1797739359682691072 |
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| author | Romana Marušić Marija Olujić Tatjana Bačun |
| author_facet | Romana Marušić Marija Olujić Tatjana Bačun |
| author_sort | Romana Marušić |
| collection | DOAJ |
| description | Pheochromocytoma is a rare cause of hypertension in pregnancy. Unrecognized, it carries a great risk for both mother and the foetus. The main reason for missing the diagnosis is the misconception that any hypertension occurring in pregnancy is gestational hypertension or pre (eclampsia). As many as 90% of patients report one or more pheochromocytoma-related symptoms antenatally, but the diagnosis is made in 75% of patients, meaning that 3 out of 10 patients are diagnosed after childbirth or post-mortem. The symptoms are similar to other more common causes of hypertension in pregnancy, which presents a major diagnostic challenge. The diagnosis is based on determination of metanephrines in plasma or 24-hour urine. Magnetic resonance imaging (MRI) and ultrasound (US) are used to localize the tumour. If the diagnosis is made before the 24th week of pregnancy, laparoscopic removal of the tumour in the second trimester is recommended. If diagnosed later, the tumour could be removed during or after delivery. Preoperative preparation with alpha blockers is required to stabilize blood pressure. The decision on the mode of delivery depends on several factors, so an experienced multidisciplinary team is needed to minimize maternal and foetal mortality. |
| first_indexed | 2024-03-12T13:56:41Z |
| format | Article |
| id | doaj.art-3d306b0a12eb46db875c330153559e54 |
| institution | Directory Open Access Journal |
| issn | 1840-0132 1840-2445 |
| language | English |
| last_indexed | 2024-03-12T13:56:41Z |
| publishDate | 2022-08-01 |
| publisher | Medical Association of Zenica-Doboj Canton |
| record_format | Article |
| series | Medicinski Glasnik |
| spelling | doaj.art-3d306b0a12eb46db875c330153559e542023-08-22T13:57:26ZengMedical Association of Zenica-Doboj CantonMedicinski Glasnik1840-01321840-24452022-08-0119210010510.17392/1474-22Pheochromocytoma in pregnancy – a rare but dangerous diagnosisRomana Marušić0Marija Olujić1Tatjana Bačun2Department of Internal Medicine, National Memorial Hospital Vukovar; School of Medicine, J. J. Strossmayer University, OsijekSchool of Medicine, J. J. Strossmayer University, Osijek; Clinical Hospital Centre, RijekaSchool of Medicine, J. J. Strossmayer University, Osijek; Department of Internal Medicine, Division of Endocrinology, University Hospital Centre, Osijek; CroatiaPheochromocytoma is a rare cause of hypertension in pregnancy. Unrecognized, it carries a great risk for both mother and the foetus. The main reason for missing the diagnosis is the misconception that any hypertension occurring in pregnancy is gestational hypertension or pre (eclampsia). As many as 90% of patients report one or more pheochromocytoma-related symptoms antenatally, but the diagnosis is made in 75% of patients, meaning that 3 out of 10 patients are diagnosed after childbirth or post-mortem. The symptoms are similar to other more common causes of hypertension in pregnancy, which presents a major diagnostic challenge. The diagnosis is based on determination of metanephrines in plasma or 24-hour urine. Magnetic resonance imaging (MRI) and ultrasound (US) are used to localize the tumour. If the diagnosis is made before the 24th week of pregnancy, laparoscopic removal of the tumour in the second trimester is recommended. If diagnosed later, the tumour could be removed during or after delivery. Preoperative preparation with alpha blockers is required to stabilize blood pressure. The decision on the mode of delivery depends on several factors, so an experienced multidisciplinary team is needed to minimize maternal and foetal mortality.https://ljkzedo.ba/mgpdf/mg37/07_Marusic_1474_A.pdfhypertensionpheochromocytomapreeclampsia |
| spellingShingle | Romana Marušić Marija Olujić Tatjana Bačun Pheochromocytoma in pregnancy – a rare but dangerous diagnosis Medicinski Glasnik hypertension pheochromocytoma preeclampsia |
| title | Pheochromocytoma in pregnancy – a rare but dangerous diagnosis |
| title_full | Pheochromocytoma in pregnancy – a rare but dangerous diagnosis |
| title_fullStr | Pheochromocytoma in pregnancy – a rare but dangerous diagnosis |
| title_full_unstemmed | Pheochromocytoma in pregnancy – a rare but dangerous diagnosis |
| title_short | Pheochromocytoma in pregnancy – a rare but dangerous diagnosis |
| title_sort | pheochromocytoma in pregnancy a rare but dangerous diagnosis |
| topic | hypertension pheochromocytoma preeclampsia |
| url | https://ljkzedo.ba/mgpdf/mg37/07_Marusic_1474_A.pdf |
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