Anemia is an independent risk for mortality after acute myocardial infarction in patients with and without diabetes
<p>Abstract</p> <p>Introduction</p> <p>Anemia and diabetes are risk factors for short-term mortality following an acute myocardial infarction(AMI). Anemia is more prevalent in patients with diabetes. We performed a retrospective study to assess the impact of the combina...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2006-04-01
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| Series: | Cardiovascular Diabetology |
| Online Access: | http://www.cardiab.com/content/5/1/8 |
| _version_ | 1828476101922390016 |
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| author | Kaiser Stephanie M Cox Jafna L O'Connell Colleen M Ransom Thomas PP Shu David H Gee Shirl A Rowe Richard C Ur Ehud Imran Syed |
| author_facet | Kaiser Stephanie M Cox Jafna L O'Connell Colleen M Ransom Thomas PP Shu David H Gee Shirl A Rowe Richard C Ur Ehud Imran Syed |
| author_sort | Kaiser Stephanie M |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Introduction</p> <p>Anemia and diabetes are risk factors for short-term mortality following an acute myocardial infarction(AMI). Anemia is more prevalent in patients with diabetes. We performed a retrospective study to assess the impact of the combination of diabetes and anemia on post-myocardial infarction outcomes.</p> <p>Methods</p> <p>Data relating to all consecutive patients hospitalized with AMI was obtained from a population-based disease-specific registry. Patients were divided into 4 groups: diabetes and anemia (group A, n = 716), diabetes and no anemia (group B, n = 1894), no diabetes and anemia (group C, n = 869), and no diabetes and no anemia (group D, n = 3987). Mortality at 30 days and 31 days to 36 months were the main outcome measures.</p> <p>Results</p> <p>30-day mortality was 32.3% in group A, 16.1% in group B, 21.5% in group C, 6.6% in group D (all p < 0.001). 31-day to 36-month mortality was 47.6% in group A, 20.8% in group B, 34.3% in group C, and 10.4% in group D (all p < 0.001). Diabetes and anemia remained independent risk factors for mortality with odds ratios of 1.61 (1.41–1.85, p < 0.001) and 1.59 (1.38–1.85, p < 0.001) respectively at 36 months. Cardiovascular death from 31-days to 36-months was 43.7% of deaths in group A, 54.1% in group B, 47.0% in group C, 50.8% group D (A vs B, p < 0.05).</p> <p>Interpretation</p> <p>Patients with both diabetes and anemia have a significantly higher mortality than those with either diabetes or anemia alone. Cardiovascular death remained the most likely cause of mortality in all groups.</p> |
| first_indexed | 2024-12-11T06:23:50Z |
| format | Article |
| id | doaj.art-3d31158ba87c4d3380c7c981306f338b |
| institution | Directory Open Access Journal |
| issn | 1475-2840 |
| language | English |
| last_indexed | 2024-12-11T06:23:50Z |
| publishDate | 2006-04-01 |
| publisher | BMC |
| record_format | Article |
| series | Cardiovascular Diabetology |
| spelling | doaj.art-3d31158ba87c4d3380c7c981306f338b2022-12-22T01:17:44ZengBMCCardiovascular Diabetology1475-28402006-04-0151810.1186/1475-2840-5-8Anemia is an independent risk for mortality after acute myocardial infarction in patients with and without diabetesKaiser Stephanie MCox Jafna LO'Connell Colleen MRansom Thomas PPShu David HGee Shirl ARowe Richard CUr EhudImran Syed<p>Abstract</p> <p>Introduction</p> <p>Anemia and diabetes are risk factors for short-term mortality following an acute myocardial infarction(AMI). Anemia is more prevalent in patients with diabetes. We performed a retrospective study to assess the impact of the combination of diabetes and anemia on post-myocardial infarction outcomes.</p> <p>Methods</p> <p>Data relating to all consecutive patients hospitalized with AMI was obtained from a population-based disease-specific registry. Patients were divided into 4 groups: diabetes and anemia (group A, n = 716), diabetes and no anemia (group B, n = 1894), no diabetes and anemia (group C, n = 869), and no diabetes and no anemia (group D, n = 3987). Mortality at 30 days and 31 days to 36 months were the main outcome measures.</p> <p>Results</p> <p>30-day mortality was 32.3% in group A, 16.1% in group B, 21.5% in group C, 6.6% in group D (all p < 0.001). 31-day to 36-month mortality was 47.6% in group A, 20.8% in group B, 34.3% in group C, and 10.4% in group D (all p < 0.001). Diabetes and anemia remained independent risk factors for mortality with odds ratios of 1.61 (1.41–1.85, p < 0.001) and 1.59 (1.38–1.85, p < 0.001) respectively at 36 months. Cardiovascular death from 31-days to 36-months was 43.7% of deaths in group A, 54.1% in group B, 47.0% in group C, 50.8% group D (A vs B, p < 0.05).</p> <p>Interpretation</p> <p>Patients with both diabetes and anemia have a significantly higher mortality than those with either diabetes or anemia alone. Cardiovascular death remained the most likely cause of mortality in all groups.</p>http://www.cardiab.com/content/5/1/8 |
| spellingShingle | Kaiser Stephanie M Cox Jafna L O'Connell Colleen M Ransom Thomas PP Shu David H Gee Shirl A Rowe Richard C Ur Ehud Imran Syed Anemia is an independent risk for mortality after acute myocardial infarction in patients with and without diabetes Cardiovascular Diabetology |
| title | Anemia is an independent risk for mortality after acute myocardial infarction in patients with and without diabetes |
| title_full | Anemia is an independent risk for mortality after acute myocardial infarction in patients with and without diabetes |
| title_fullStr | Anemia is an independent risk for mortality after acute myocardial infarction in patients with and without diabetes |
| title_full_unstemmed | Anemia is an independent risk for mortality after acute myocardial infarction in patients with and without diabetes |
| title_short | Anemia is an independent risk for mortality after acute myocardial infarction in patients with and without diabetes |
| title_sort | anemia is an independent risk for mortality after acute myocardial infarction in patients with and without diabetes |
| url | http://www.cardiab.com/content/5/1/8 |
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