Effects of Metalloporphyrins on Heme Oxygenase-1 Transcription: Correlative Cell Culture Assays Guide in Vivo Imaging

Effects of Metalloporphyrins on Heme Oxygenase-1 Transcription: Correlative Cell Culture Assays Guide in Vivo Imaging

Heme oxygenase (HO) is the rate-limiting step in the heme degradation pathway and is a potential target for the control, or prevention, of pathologic jaundice in neonates. Metalloporphyrins (Mps), a diverse set of synthetic derivatives of heme, can competitively inhibit the HO enzymes. However, cert...

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Bibliographic Details
Main Authors:	Monica Hajdena-Dawson, Weisheng Zhang, Pamela R. Contag, Ronald J. Wong, Hendrik J. Vreman, David K. Stevenson, Christopher H. Contag
Format:	Article
Language:	English
Published:	SAGE Publications 2003-07-01
Series:	Molecular Imaging
Online Access:	https://doi.org/10.1162/15353500200303139

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