Particulate matter and childhood allergic diseases

Particulate matter (PM) is a ubiquitous air pollutant that is a growing public health concern. Previous studies have suggested that PM is associated with asthma development and exacerbation of asthma symptoms. Although several studies have suggested increased risks of atopic dermatitis, allergic rhi...

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Main Author: Song-I Yang
Format: Article
Language:English
Published: Korean Pediatric Society 2019-01-01
Series:Korean Journal of Pediatrics
Subjects:
Online Access:http://www.kjp.or.kr/upload/pdf/kjp-2018-07045.pdf
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author Song-I Yang
author_facet Song-I Yang
author_sort Song-I Yang
collection DOAJ
description Particulate matter (PM) is a ubiquitous air pollutant that is a growing public health concern. Previous studies have suggested that PM is associated with asthma development and exacerbation of asthma symptoms. Although several studies have suggested increased risks of atopic dermatitis, allergic rhinitis, and allergic sensitization in relation to PM exposure, the evidence remains inconsistent. The plausible mechanisms underlying these effects are related to oxidative stress, enhancement of sensitization to allergens, inflammatory and immunological responses, and epigenetics. This review discusses the effect of PM on childhood allergic diseases, along with plausible mechanisms. Further studies are required to understand the role of PM exposure on childhood allergic diseases, to reduce these diseases in children.
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spelling doaj.art-3d346defc30c41dbac2641457564b9f22022-12-21T18:42:27ZengKorean Pediatric SocietyKorean Journal of Pediatrics1738-10612092-72582019-01-01621222910.3345/kjp.2018.0704520125553496Particulate matter and childhood allergic diseasesSong-I Yang0 Department of Pediatrics, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, KoreaParticulate matter (PM) is a ubiquitous air pollutant that is a growing public health concern. Previous studies have suggested that PM is associated with asthma development and exacerbation of asthma symptoms. Although several studies have suggested increased risks of atopic dermatitis, allergic rhinitis, and allergic sensitization in relation to PM exposure, the evidence remains inconsistent. The plausible mechanisms underlying these effects are related to oxidative stress, enhancement of sensitization to allergens, inflammatory and immunological responses, and epigenetics. This review discusses the effect of PM on childhood allergic diseases, along with plausible mechanisms. Further studies are required to understand the role of PM exposure on childhood allergic diseases, to reduce these diseases in children.http://www.kjp.or.kr/upload/pdf/kjp-2018-07045.pdfparticulate matterasthmaallergychild
spellingShingle Song-I Yang
Particulate matter and childhood allergic diseases
Korean Journal of Pediatrics
particulate matter
asthma
allergy
child
title Particulate matter and childhood allergic diseases
title_full Particulate matter and childhood allergic diseases
title_fullStr Particulate matter and childhood allergic diseases
title_full_unstemmed Particulate matter and childhood allergic diseases
title_short Particulate matter and childhood allergic diseases
title_sort particulate matter and childhood allergic diseases
topic particulate matter
asthma
allergy
child
url http://www.kjp.or.kr/upload/pdf/kjp-2018-07045.pdf
work_keys_str_mv AT songiyang particulatematterandchildhoodallergicdiseases