A linear model for transcription factor binding affinity prediction in protein binding microarrays.

A linear model for transcription factor binding affinity prediction in protein binding microarrays.

Protein binding microarrays (PBM) are a high throughput technology used to characterize protein-DNA binding. The arrays measure a protein's affinity toward thousands of double-stranded DNA sequences at once, producing a comprehensive binding specificity catalog. We present a linear model for pr...

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Bibliographic Details
Main Authors:	Matti Annala, Kirsti Laurila, Harri Lähdesmäki, Matti Nykter
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2011-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC3102690?pdf=render

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