Programmed Death-Ligand 1 Expression in Lung Cancer and Paired Brain Metastases—a Single-Center Study in 190 Patients

Programmed Death-Ligand 1 Expression in Lung Cancer and Paired Brain Metastases—a Single-Center Study in 190 Patients

Introduction: Expression of programmed death-ligand 1 (PD-L1) is the only routinely used tissue biomarker for predicting response to programmed cell death protein 1/PD-L1 inhibitors. It is to date unclear whether PD-L1 expression is preserved in brain metastases (BMs). Methods: In this single-center...

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Bibliographic Details
Main Authors: Alexandra Kündig, MMed, Philipp Zens, MD, Christian Fung, MD, Amina Scherz, MD, Ferdinando Cerciello, MD, PhD, Evelyn Herrmann, MD, Ekin Ermis, MD, Ralph A. Schmid, MD, Erik Vassella, PhD, Sabina Berezowska, MD
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:JTO Clinical and Research Reports
Subjects:
Brain metastasis
Lung cancer
NSCLC
PD-L1
Immune checkpoint inhibitors
Online Access:http://www.sciencedirect.com/science/article/pii/S2666364322001370

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http://www.sciencedirect.com/science/article/pii/S2666364322001370

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