A newly synthesized platinum-based compound (PBC-II) increases chemosensitivity of HeLa ovarian cancer cells via inhibition of autophagy

A newly synthesized platinum-based compound (PBC-II) increases chemosensitivity of HeLa ovarian cancer cells via inhibition of autophagy

There are many mechanisms of resistance, chemoresistance of HeLa cells to anti-cancer agents seems to be autophagy-mediated. While using very effective anti-cancers such as Doxorubicin and cisplatin, cells overcome the cytotoxicity of these drugs through promotion of what so-called cytoprotective au...

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Bibliographic Details
Main Authors: Moureq Rashed Alotaibi, Homood Moqbel As Sobeai, Faten Abdullah Alaqil, Mashal Almutairi, Khalid Alhazzani, Adam A.A. Sulaiman, Anvarhusein A. Isab, Nasser Hadal Alotaibi
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Saudi Pharmaceutical Journal
Online Access:http://www.sciencedirect.com/science/article/pii/S131901641930132X

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