Hepatobiliary Involvement in Neonates With COVID-19 Infection: A Previous Case Series Studies
Background: The most common symptoms in neonates with severe COVID-19 infection have been respiratory problems. The virus may adversely affect organs such as the liver. Methods: Studies focusing solely on liver involvement in newborns with COVID-19 infection were searched in Pubmed, Scopus, and Goo...
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| Format: | Article |
| Language: | English |
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Mazandaran University of Medical Sciences
2023-04-01
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| Series: | Journal of Pediatrics Review |
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| Online Access: | http://jpr.mazums.ac.ir/article-1-498-en.pdf |
| _version_ | 1797801896138768384 |
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| author | Roya Farhadi |
| author_facet | Roya Farhadi |
| author_sort | Roya Farhadi |
| collection | DOAJ |
| description | Background: The most common symptoms in neonates with severe COVID-19 infection have been respiratory problems. The virus may adversely affect organs such as the liver.
Methods: Studies focusing solely on liver involvement in newborns with COVID-19 infection were searched in Pubmed, Scopus, and Google Scholar databases. Eight studies were finally reviewed.
Results: Direct viral invasion (COVID-19-induced hepatitis or systemic inflammatory response) and drug-induced may contribute to liver damage in neonates. SARS-CoV-2 may be the latest spark in toxoplasmosis, other agents, rubella, cytomegalovirus, herpes infections, and fetal liver involvement may be induced by transplacental transmission.
Conclusions: Hepatic dysfunction is infrequent but important in neonates with COVID-19 infection and the mechanism of liver damage associated with COVID-19 may differ from that in adults. |
| first_indexed | 2024-03-13T04:58:31Z |
| format | Article |
| id | doaj.art-3d389bf6c9ad4d41a2f182d7ffa90bbc |
| institution | Directory Open Access Journal |
| issn | 2322-4398 2322-4401 |
| language | English |
| last_indexed | 2024-03-13T04:58:31Z |
| publishDate | 2023-04-01 |
| publisher | Mazandaran University of Medical Sciences |
| record_format | Article |
| series | Journal of Pediatrics Review |
| spelling | doaj.art-3d389bf6c9ad4d41a2f182d7ffa90bbc2023-06-17T10:29:15ZengMazandaran University of Medical SciencesJournal of Pediatrics Review2322-43982322-44012023-04-01112125134Hepatobiliary Involvement in Neonates With COVID-19 Infection: A Previous Case Series StudiesRoya Farhadi0 Pediatric Infectious Diseases Research Center, Mazandaran University of Medical Sciences, Sari, Iran. Background: The most common symptoms in neonates with severe COVID-19 infection have been respiratory problems. The virus may adversely affect organs such as the liver. Methods: Studies focusing solely on liver involvement in newborns with COVID-19 infection were searched in Pubmed, Scopus, and Google Scholar databases. Eight studies were finally reviewed. Results: Direct viral invasion (COVID-19-induced hepatitis or systemic inflammatory response) and drug-induced may contribute to liver damage in neonates. SARS-CoV-2 may be the latest spark in toxoplasmosis, other agents, rubella, cytomegalovirus, herpes infections, and fetal liver involvement may be induced by transplacental transmission. Conclusions: Hepatic dysfunction is infrequent but important in neonates with COVID-19 infection and the mechanism of liver damage associated with COVID-19 may differ from that in adults.http://jpr.mazums.ac.ir/article-1-498-en.pdfcovid-19hepatitisliver diseasesnewbornsars-cov-2transaminases |
| spellingShingle | Roya Farhadi Hepatobiliary Involvement in Neonates With COVID-19 Infection: A Previous Case Series Studies Journal of Pediatrics Review covid-19 hepatitis liver diseases newborn sars-cov-2 transaminases |
| title | Hepatobiliary Involvement in Neonates With COVID-19 Infection: A Previous Case Series Studies |
| title_full | Hepatobiliary Involvement in Neonates With COVID-19 Infection: A Previous Case Series Studies |
| title_fullStr | Hepatobiliary Involvement in Neonates With COVID-19 Infection: A Previous Case Series Studies |
| title_full_unstemmed | Hepatobiliary Involvement in Neonates With COVID-19 Infection: A Previous Case Series Studies |
| title_short | Hepatobiliary Involvement in Neonates With COVID-19 Infection: A Previous Case Series Studies |
| title_sort | hepatobiliary involvement in neonates with covid 19 infection a previous case series studies |
| topic | covid-19 hepatitis liver diseases newborn sars-cov-2 transaminases |
| url | http://jpr.mazums.ac.ir/article-1-498-en.pdf |
| work_keys_str_mv | AT royafarhadi hepatobiliaryinvolvementinneonateswithcovid19infectionapreviouscaseseriesstudies |