Focal structural variants revealed by whole genome sequencing disrupt the histone demethylase KDM4C in B-cell lymphomas
Histone methylation-modifiers, such as EZH2 and KMT2D, are recurrently altered in B-cell lymphomas. To comprehensively describe the landscape of alterations affecting genes encoding histone methylation-modifiers in lymphomagenesis we investigated whole genome and transcriptome data of 186 mature B-...
Հիմնական հեղինակներ: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Ձևաչափ: | Հոդված |
Լեզու: | English |
Հրապարակվել է: |
Ferrata Storti Foundation
2022-04-01
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Շարք: | Haematologica |
Առցանց հասանելիություն: | https://haematologica.org/article/view/10618 |