CX3CR1 is expressed by human B lymphocytes and mediates [corrected] CX3CL1 driven chemotaxis of tonsil centrocytes.

CX3CR1 is expressed by human B lymphocytes and mediates [corrected] CX3CL1 driven chemotaxis of tonsil centrocytes.

BACKGROUND:Fractalkine/CX(3)CL1, a surface chemokine, binds to CX(3)CR1 expressed by different lymphocyte subsets. Since CX(3)CL1 has been detected in the germinal centres of secondary lymphoid tissue, in this study we have investigated CX(3)CR1 expression and function in human naïve, germinal centr...

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Main Authors: Anna Corcione, Elisa Ferretti, Maria Bertolotto, Franco Fais, Lizzia Raffaghello, Andrea Gregorio, Claudya Tenca, Luciano Ottonello, Claudio Gambini, Glaucia Furtado, Sergio Lira, Vito Pistoia
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-12-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2793522?pdf=render

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