Relation between safe use of medicines and Clinical Pharmacy Services at Pediatric Intensive Care Units

Abstract Objective: Clinical Pharmacy Services (CPS) are considered standard of care and is endorsed by the Joint Commission International, the American Academy of Pediatrics, and the American College of Clinical Pharmacy. In Brazil, single experiences have been discreetly arising and the importanc...

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Main Authors: Lucas Miyake Okumura, Daniella Matsubara da Silva, Larissa Comarella
Format: Article
Language:English
Published: Sociedade de Pediatria de São Paulo
Series:Revista Paulista de Pediatria
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-05822016000400397&lng=en&tlng=en
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author Lucas Miyake Okumura
Daniella Matsubara da Silva
Larissa Comarella
author_facet Lucas Miyake Okumura
Daniella Matsubara da Silva
Larissa Comarella
author_sort Lucas Miyake Okumura
collection DOAJ
description Abstract Objective: Clinical Pharmacy Services (CPS) are considered standard of care and is endorsed by the Joint Commission International, the American Academy of Pediatrics, and the American College of Clinical Pharmacy. In Brazil, single experiences have been discreetly arising and the importance of these services to children and adolescents care has led to interesting results, but certainly are under reported. This short report aims to discuss the effect of implementing a bedside CPS at a Brazilian Pediatric Intensive Care Unit (PICU). Methods: This is a cross-sectional study conducted in a 12 bed PICU community hospital, from Campo Largo/Brazil. Subjects with<18 years old admitted to PICU were included for descriptive analysis if received a CPS intervention. Results: Of 53 patients accompanied, we detected 141 preventable drug-related problems (DRPs) which were solved within clinicians (89% acceptance of all interventions). The most common interventions performed to improve drug therapy included: preventing incompatible intravenous solutions (21%) and a composite of inadequate doses (17% due to low, high and non-optimized doses). Among the top ten medications associated with DRPs, five were antimicrobials. By analyzing the correlation between DRPs and PICU length of stay, we found that 74% of all variations on length of stay were associated with the number of DRPs. Conclusions: Adverse drug reactions due to avoidable DRPs can be prevented by CPS in a multifaceted collaboration with other health care professionals, who should attempt to use active and evidence-based strategies to reduce morbidity related to medications.
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spelling doaj.art-3d3d8948920648a592ee32dcaa899a0d2022-12-21T23:13:02ZengSociedade de Pediatria de São PauloRevista Paulista de Pediatria1984-046234439740210.1016/j.rppede.2016.04.001S0103-05822016000400397Relation between safe use of medicines and Clinical Pharmacy Services at Pediatric Intensive Care UnitsLucas Miyake OkumuraDaniella Matsubara da SilvaLarissa ComarellaAbstract Objective: Clinical Pharmacy Services (CPS) are considered standard of care and is endorsed by the Joint Commission International, the American Academy of Pediatrics, and the American College of Clinical Pharmacy. In Brazil, single experiences have been discreetly arising and the importance of these services to children and adolescents care has led to interesting results, but certainly are under reported. This short report aims to discuss the effect of implementing a bedside CPS at a Brazilian Pediatric Intensive Care Unit (PICU). Methods: This is a cross-sectional study conducted in a 12 bed PICU community hospital, from Campo Largo/Brazil. Subjects with<18 years old admitted to PICU were included for descriptive analysis if received a CPS intervention. Results: Of 53 patients accompanied, we detected 141 preventable drug-related problems (DRPs) which were solved within clinicians (89% acceptance of all interventions). The most common interventions performed to improve drug therapy included: preventing incompatible intravenous solutions (21%) and a composite of inadequate doses (17% due to low, high and non-optimized doses). Among the top ten medications associated with DRPs, five were antimicrobials. By analyzing the correlation between DRPs and PICU length of stay, we found that 74% of all variations on length of stay were associated with the number of DRPs. Conclusions: Adverse drug reactions due to avoidable DRPs can be prevented by CPS in a multifaceted collaboration with other health care professionals, who should attempt to use active and evidence-based strategies to reduce morbidity related to medications.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-05822016000400397&lng=en&tlng=enCuidados intensivosEfeitos colaterais relacionados a medicamentos e reações adversasUnidades de Cuidado Intensivo PediátricoServiço de Farmácia, HospitalSegurança do pacienteErros de medicação
spellingShingle Lucas Miyake Okumura
Daniella Matsubara da Silva
Larissa Comarella
Relation between safe use of medicines and Clinical Pharmacy Services at Pediatric Intensive Care Units
Revista Paulista de Pediatria
Cuidados intensivos
Efeitos colaterais relacionados a medicamentos e reações adversas
Unidades de Cuidado Intensivo Pediátrico
Serviço de Farmácia, Hospital
Segurança do paciente
Erros de medicação
title Relation between safe use of medicines and Clinical Pharmacy Services at Pediatric Intensive Care Units
title_full Relation between safe use of medicines and Clinical Pharmacy Services at Pediatric Intensive Care Units
title_fullStr Relation between safe use of medicines and Clinical Pharmacy Services at Pediatric Intensive Care Units
title_full_unstemmed Relation between safe use of medicines and Clinical Pharmacy Services at Pediatric Intensive Care Units
title_short Relation between safe use of medicines and Clinical Pharmacy Services at Pediatric Intensive Care Units
title_sort relation between safe use of medicines and clinical pharmacy services at pediatric intensive care units
topic Cuidados intensivos
Efeitos colaterais relacionados a medicamentos e reações adversas
Unidades de Cuidado Intensivo Pediátrico
Serviço de Farmácia, Hospital
Segurança do paciente
Erros de medicação
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-05822016000400397&lng=en&tlng=en
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