Diminished HIV Infection of Target CD4+ T Cells in a Toll-Like Receptor 4 Stimulated in vitro Model

Diminished HIV Infection of Target CD4+ T Cells in a Toll-Like Receptor 4 Stimulated in vitro Model

Genital inflammation is associated with increased HIV acquisition risk. Induction of an inflammatory response can occur through the recognition of pathogenic or commensal microbes by Toll-like receptors (TLRs) on various immune cells. We used a in vitro peripheral blood mononuclear cell (PBMC) syste...

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Bibliographic Details
Main Authors: Ross Cromarty, Alex Sigal, Lenine J. P. Liebenberg, Lyle R. McKinnon, Salim S. Abdool Karim, Jo-Ann S. Passmore, Derseree Archary
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Immunology
Subjects:
Toll-like receptors
inflammation
immune activation
HIV
cytokines
innate antiviral immunity
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01705/full

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