Competitive fitness of Pseudomonas aeruginosa isolates in human and murine precision-cut lung slices

Competitive fitness of Pseudomonas aeruginosa isolates in human and murine precision-cut lung slices

Chronic respiratory infections with the gram-negative bacterium Pseudomonas aeruginosa are an important co-morbidity for the quality of life and prognosis of people with cystic fibrosis (CF). Such long-term colonization, sometimes lasting up to several decades, represents a unique opportunity to inv...

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Bibliographic Details
Main Authors: Nina Cramer, Marie Luise Nawrot, Lion Wege, Marie Dorda, Charline Sommer, Olga Danov, Sabine Wronski, Armin Braun, Danny Jonigk, Sebastian Fischer, Antje Munder, Burkhard Tümmler
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
chronic bacterial infection
cystic fibrosis
pseudomonas aeruginosa
adaptation
host defense
precision-cut lung slices
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2022.992214/full

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