Evaluation of optic nerve in patients with acute primary angle-closure glaucoma
AIM: To evaluate the damage to optic nerve by detecting the morphological and functional changes of optic nerve in patients with acute primary angle-closure glaucoma.METHODS: The correlation among the positive rates of fundus photography, visual field examination, optical coherence tomography(OCT)sc...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Press of International Journal of Ophthalmology (IJO PRESS)
2023-08-01
|
| Series: | Guoji Yanke Zazhi |
| Subjects: | |
| Online Access: | http://ies.ijo.cn/cn_publish/2023/8/202308029.pdf |
| _version_ | 1797773068090736640 |
|---|---|
| author | Ming-Bao Gou Quan-Liang Zhao Fang Yuan Yan Sun |
| author_facet | Ming-Bao Gou Quan-Liang Zhao Fang Yuan Yan Sun |
| author_sort | Ming-Bao Gou |
| collection | DOAJ |
| description | AIM: To evaluate the damage to optic nerve by detecting the morphological and functional changes of optic nerve in patients with acute primary angle-closure glaucoma.METHODS: The correlation among the positive rates of fundus photography, visual field examination, optical coherence tomography(OCT)scan of the optic nerve, and pattern visual evoked potentials(P-VEP)were analyzed in 28 patients with acute primary angle-closure glaucoma affecting.RESULTS: Among 28 eyes of 28 patients, optic nerve images were obtained in 25 eyes(89%), optic disc color in 25 eyes: there were 9 normal eyes and 16 eyes with congestion and edema, without pallor; C/D: < 0.6 in 5 eyes, > 0.6 in 1 eye, and indistinguishable in 19 eyes; disk edge: 6 eyes were normal, and 19 eyes could not be distinguished.Optic nerve images could not be obtained in 3 eyes(11%). Visual field examination: 9 eyes(32%)were normal, 2 eyes(7%)had visual field damage, 8 eyes(29%)had no reference value due to cataract visual field examination, 2 eyes(7%)had false positive rate ≥15%, and 7 eyes(25%)could not cooperate with the examination. The retinal nerve fiber layer thickness around optic disc was measured by OCT in 26 eyes(93%), of which the thickness of nerve fiber layer was normal in 24 eyes and local thinning in 2 eyes. Severe opacification of refractive stroma could not be measured in 2 eyes(7%). PVEP showed that the peak of P100 was normal in 18 eyes(64%)and prolonged in 10 eyes(36%). The amplitude of P100 wave was normal in 11 eyes(39%)and decreased in 17 eyes(61%).CONCLUSION: After a major acute attack of primary angle-closure glaucoma, the optic nerve does not exhibit typical glaucomatous damage but may present with optic disc congestion and edema. Therefore, a comprehensive evaluation combining subjective and objective examination methods is necessary for optic nerve assessment, and currently, no more precise assessment method is available. |
| first_indexed | 2024-03-12T21:59:50Z |
| format | Article |
| id | doaj.art-3d498e600c8d4fcd88f4fef47a1437dc |
| institution | Directory Open Access Journal |
| issn | 1672-5123 |
| language | English |
| last_indexed | 2024-03-12T21:59:50Z |
| publishDate | 2023-08-01 |
| publisher | Press of International Journal of Ophthalmology (IJO PRESS) |
| record_format | Article |
| series | Guoji Yanke Zazhi |
| spelling | doaj.art-3d498e600c8d4fcd88f4fef47a1437dc2023-07-25T08:31:59ZengPress of International Journal of Ophthalmology (IJO PRESS)Guoji Yanke Zazhi1672-51232023-08-012381390139410.3980/j.issn.1672-5123.2023.8.29202308029Evaluation of optic nerve in patients with acute primary angle-closure glaucomaMing-Bao Gou0Quan-Liang Zhao1Fang Yuan2Yan Sun3Department of Ophthalmology, Inner Mongolia Forestry General Hospital, Yakeshi 022150, Inner Mongolia Autonomous Region, ChinaDepartment of Ophthalmology, Inner Mongolia Forestry General Hospital, Yakeshi 022150, Inner Mongolia Autonomous Region, ChinaDepartment of Ophthalmology, Inner Mongolia Forestry General Hospital, Yakeshi 022150, Inner Mongolia Autonomous Region, ChinaDepartment of Ophthalmology, Inner Mongolia Forestry General Hospital, Yakeshi 022150, Inner Mongolia Autonomous Region, ChinaAIM: To evaluate the damage to optic nerve by detecting the morphological and functional changes of optic nerve in patients with acute primary angle-closure glaucoma.METHODS: The correlation among the positive rates of fundus photography, visual field examination, optical coherence tomography(OCT)scan of the optic nerve, and pattern visual evoked potentials(P-VEP)were analyzed in 28 patients with acute primary angle-closure glaucoma affecting.RESULTS: Among 28 eyes of 28 patients, optic nerve images were obtained in 25 eyes(89%), optic disc color in 25 eyes: there were 9 normal eyes and 16 eyes with congestion and edema, without pallor; C/D: < 0.6 in 5 eyes, > 0.6 in 1 eye, and indistinguishable in 19 eyes; disk edge: 6 eyes were normal, and 19 eyes could not be distinguished.Optic nerve images could not be obtained in 3 eyes(11%). Visual field examination: 9 eyes(32%)were normal, 2 eyes(7%)had visual field damage, 8 eyes(29%)had no reference value due to cataract visual field examination, 2 eyes(7%)had false positive rate ≥15%, and 7 eyes(25%)could not cooperate with the examination. The retinal nerve fiber layer thickness around optic disc was measured by OCT in 26 eyes(93%), of which the thickness of nerve fiber layer was normal in 24 eyes and local thinning in 2 eyes. Severe opacification of refractive stroma could not be measured in 2 eyes(7%). PVEP showed that the peak of P100 was normal in 18 eyes(64%)and prolonged in 10 eyes(36%). The amplitude of P100 wave was normal in 11 eyes(39%)and decreased in 17 eyes(61%).CONCLUSION: After a major acute attack of primary angle-closure glaucoma, the optic nerve does not exhibit typical glaucomatous damage but may present with optic disc congestion and edema. Therefore, a comprehensive evaluation combining subjective and objective examination methods is necessary for optic nerve assessment, and currently, no more precise assessment method is available.http://ies.ijo.cn/cn_publish/2023/8/202308029.pdfacute primary angle-closure glaucomahigh intraocular pressureoptic nerve |
| spellingShingle | Ming-Bao Gou Quan-Liang Zhao Fang Yuan Yan Sun Evaluation of optic nerve in patients with acute primary angle-closure glaucoma Guoji Yanke Zazhi acute primary angle-closure glaucoma high intraocular pressure optic nerve |
| title | Evaluation of optic nerve in patients with acute primary angle-closure glaucoma |
| title_full | Evaluation of optic nerve in patients with acute primary angle-closure glaucoma |
| title_fullStr | Evaluation of optic nerve in patients with acute primary angle-closure glaucoma |
| title_full_unstemmed | Evaluation of optic nerve in patients with acute primary angle-closure glaucoma |
| title_short | Evaluation of optic nerve in patients with acute primary angle-closure glaucoma |
| title_sort | evaluation of optic nerve in patients with acute primary angle closure glaucoma |
| topic | acute primary angle-closure glaucoma high intraocular pressure optic nerve |
| url | http://ies.ijo.cn/cn_publish/2023/8/202308029.pdf |
| work_keys_str_mv | AT mingbaogou evaluationofopticnerveinpatientswithacuteprimaryangleclosureglaucoma AT quanliangzhao evaluationofopticnerveinpatientswithacuteprimaryangleclosureglaucoma AT fangyuan evaluationofopticnerveinpatientswithacuteprimaryangleclosureglaucoma AT yansun evaluationofopticnerveinpatientswithacuteprimaryangleclosureglaucoma |