Discrepancy between Lung Function Measurements at Home and in the Hospital in Children with Asthma and CF
The Coronavirus pandemic stresses the importance of eHealth techniques to monitor patients at home. Home monitoring of lung function in asthma and cystic fibrosis (CF) may help to detect deterioration of lung function at an early stage, but the reliability is unclear. We investigated whether lung fu...
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| Format: | Article |
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MDPI AG
2020-05-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/9/6/1617 |
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| author | Frederick L.G.R. Gerzon Quirijn Jöbsis Michiel A.G.E. Bannier Bjorn Winkens Edward Dompeling |
| author_facet | Frederick L.G.R. Gerzon Quirijn Jöbsis Michiel A.G.E. Bannier Bjorn Winkens Edward Dompeling |
| author_sort | Frederick L.G.R. Gerzon |
| collection | DOAJ |
| description | The Coronavirus pandemic stresses the importance of eHealth techniques to monitor patients at home. Home monitoring of lung function in asthma and cystic fibrosis (CF) may help to detect deterioration of lung function at an early stage, but the reliability is unclear. We investigated whether lung function measurements at home were comparable to measurements during clinical visits. We analysed prospectively collected data of two one-year observational cohort studies in 117 children (36 with CF and 81 with asthma). All patients performed forced expiratory volume in one second (FEV<sub>1</sub>) measurements with a monitor at home. Paired FEV<sub>1</sub> measurements were included if the measurement on the home monitor was performed on the same day as the FEV<sub>1</sub> measurement on the pneumotachometer during a two monthly clinical visit. Bland-Altman plots and linear mixed model analysis were used. The mean difference (home measurement was subtracted from clinical measurement) in FEV<sub>1</sub> was 0.18 L in CF (95% confidence interval (CI) 0.08–0.27 L; <i>p</i> < 0.001) and 0.12 L in asthma (95%CI 0.05–0.19 L; <i>p</i> < 0.001). FEV<sub>1</sub> measurements at home were significantly lower than clinically obtained FEV<sub>1</sub> measurements, which has implications for the application of this technique in the daily clinical situation. |
| first_indexed | 2024-03-10T19:34:31Z |
| format | Article |
| id | doaj.art-3d49b4cb9a3346c3a2013014c9ec2347 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-10T19:34:31Z |
| publishDate | 2020-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-3d49b4cb9a3346c3a2013014c9ec23472023-11-20T01:50:26ZengMDPI AGJournal of Clinical Medicine2077-03832020-05-0196161710.3390/jcm9061617Discrepancy between Lung Function Measurements at Home and in the Hospital in Children with Asthma and CFFrederick L.G.R. Gerzon0Quirijn Jöbsis1Michiel A.G.E. Bannier2Bjorn Winkens3Edward Dompeling4Department of Paediatric Pulmonology, School for Public Health and Primary Care (CAPHRI), Maastricht University Medical Centre (MUMC+), 6202 AZ Maastricht, The NetherlandsDepartment of Paediatric Pulmonology, School for Public Health and Primary Care (CAPHRI), Maastricht University Medical Centre (MUMC+), 6202 AZ Maastricht, The NetherlandsDepartment of Paediatric Pulmonology, School for Public Health and Primary Care (CAPHRI), Maastricht University Medical Centre (MUMC+), 6202 AZ Maastricht, The NetherlandsDepartment of Methodology and Statistics, CAPHRI, MUMC+, 6229 HA Maastricht, The NetherlandsDepartment of Paediatric Pulmonology, School for Public Health and Primary Care (CAPHRI), Maastricht University Medical Centre (MUMC+), 6202 AZ Maastricht, The NetherlandsThe Coronavirus pandemic stresses the importance of eHealth techniques to monitor patients at home. Home monitoring of lung function in asthma and cystic fibrosis (CF) may help to detect deterioration of lung function at an early stage, but the reliability is unclear. We investigated whether lung function measurements at home were comparable to measurements during clinical visits. We analysed prospectively collected data of two one-year observational cohort studies in 117 children (36 with CF and 81 with asthma). All patients performed forced expiratory volume in one second (FEV<sub>1</sub>) measurements with a monitor at home. Paired FEV<sub>1</sub> measurements were included if the measurement on the home monitor was performed on the same day as the FEV<sub>1</sub> measurement on the pneumotachometer during a two monthly clinical visit. Bland-Altman plots and linear mixed model analysis were used. The mean difference (home measurement was subtracted from clinical measurement) in FEV<sub>1</sub> was 0.18 L in CF (95% confidence interval (CI) 0.08–0.27 L; <i>p</i> < 0.001) and 0.12 L in asthma (95%CI 0.05–0.19 L; <i>p</i> < 0.001). FEV<sub>1</sub> measurements at home were significantly lower than clinically obtained FEV<sub>1</sub> measurements, which has implications for the application of this technique in the daily clinical situation.https://www.mdpi.com/2077-0383/9/6/1617home monitoringlung functionasthmacystic fibrosischildrentelemedicine |
| spellingShingle | Frederick L.G.R. Gerzon Quirijn Jöbsis Michiel A.G.E. Bannier Bjorn Winkens Edward Dompeling Discrepancy between Lung Function Measurements at Home and in the Hospital in Children with Asthma and CF Journal of Clinical Medicine home monitoring lung function asthma cystic fibrosis children telemedicine |
| title | Discrepancy between Lung Function Measurements at Home and in the Hospital in Children with Asthma and CF |
| title_full | Discrepancy between Lung Function Measurements at Home and in the Hospital in Children with Asthma and CF |
| title_fullStr | Discrepancy between Lung Function Measurements at Home and in the Hospital in Children with Asthma and CF |
| title_full_unstemmed | Discrepancy between Lung Function Measurements at Home and in the Hospital in Children with Asthma and CF |
| title_short | Discrepancy between Lung Function Measurements at Home and in the Hospital in Children with Asthma and CF |
| title_sort | discrepancy between lung function measurements at home and in the hospital in children with asthma and cf |
| topic | home monitoring lung function asthma cystic fibrosis children telemedicine |
| url | https://www.mdpi.com/2077-0383/9/6/1617 |
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