Pharmacokinetics of Hydroxyprogesterone Caproate and its Primary Metabolites during Pregnancy

Pharmacokinetics of Hydroxyprogesterone Caproate and its Primary Metabolites during Pregnancy

Abstract Objective To measure pharmacokinetics of hydroxyprogesterone caproate (OHPC) and its major metabolites throughout pregnancy. Study Design Thirty women were prescribed OHPC for recurrent preterm birth prevention. Three cohorts of subjects had blood drawn for 7 conse...

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Bibliographic Details
Main Authors: Kim A. Boggess, Jeffrey B. Baker, Amy P. Murtha, Alan M. Peaceman, Dinesh M. Shah, Sylvia L. Siegfried, Robert Birch
Format: Article
Language:English
Published: Thieme Medical Publishers, Inc. 2018-04-01
Series:American Journal of Perinatology Reports
Subjects:
gestation
hydroxyprogesterone
metabolites
pharmacokinetics
pregnancy
preterm birth
Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0038-1639331

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